Recent research has demonstrated that survivors of childhood cancer are at risk for a myriad
of late effects that affect physical and mental quality of life. We discuss the patterns and …

The intensified administration of chemotherapeutic drugs has gradually replaced cranial
radiation therapy (CRT) for the treatment of childhood acute lymphoblastic leukemia (ALL) …

Chemotherapy results in a frequent yet poorly understood syndrome of long-term
neurological deficits. Neural precursor cell dysfunction and white matter dysfunction are …

Activity-dependent myelination is thought to contribute to adaptive neurological function.
However, the mechanisms by which activity regulates myelination and the extent to which …

In recent years, graph theoretical analyses of neuroimaging data have increased our
understanding of the organization of large-scale structural and functional brain networks …

Primary objectives: Children with a history of cancer are at increased risk for cognitive
impairments, particularly in executive and memory domains. Traditional, in-person cognitive …

Survivors of childhood cancer frequently experience cancer-related cognitive dysfunction,
commonly months to years after treatment for pediatric brain tumors, acute lymphoblastic …

Aim This meta‐analysis provides a systematic review of studies into intellectual and
attentional functioning of paediatric brain tumour survivors (PBTS) as assessed by two …

PURPOSE Many children treated for ALL develop long-term neurocognitive impairments.
Increased risk of these impairments is associated with treatment and demographic factors …

Objective In children, CNS‐directed cancer therapy is thought to result in decreased
cerebral white matter volumes (WMV) and subsequent neurocognitive deficits. This study …