Isothermal nucleic acid amplification technologies for point-of-care diagnostics: a critical review

P Craw, W Balachandran - Lab on a Chip, 2012 - pubs.rsc.org
Nucleic Acid Testing (NAT) promises rapid, sensitive and specific diagnosis of infectious,
inherited and genetic disease. The next generation of diagnostic devices will interrogate the …

Point-of-care nucleic acid testing for infectious diseases

A Niemz, TM Ferguson, DS Boyle - Trends in biotechnology, 2011 - cell.com
Nucleic acid testing for infectious diseases at the point of care is beginning to enter clinical
practice in developed and develo** countries; especially for applications requiring fast …

Soft lithography for micro-and nanoscale patterning

D Qin, Y **a, GM Whitesides - Nature protocols, 2010 - nature.com
This protocol provides an introduction to soft lithography—a collection of techniques based
on printing, molding and embossing with an elastomeric stamp. Soft lithography provides …

Microfluidic devices for bioapplications

LY Yeo, HC Chang, PPY Chan, JR Friend - small, 2011 - Wiley Online Library
Harnessing the ability to precisely and reproducibly actuate fluids and manipulate
bioparticles such as DNA, cells, and molecules at the microscale, microfluidics is a powerful …

Micromixing within microfluidic devices

L Capretto, W Cheng, M Hill, X Zhang - Microfluidics: technologies and …, 2011 - Springer
Micromixing is a crucial process within microfluidic systems such as micro total analysis
systems (μTAS). A state-of-art review on microstructured mixing devices and their mixing …

Next-generation sequencing in the clinic: promises and challenges

J Xuan, Y Yu, T Qing, L Guo, L Shi - Cancer letters, 2013 - Elsevier
The advent of next generation sequencing (NGS) technologies has revolutionized the field
of genomics, enabling fast and cost-effective generation of genome-scale sequence data …

Miniaturized isothermal nucleic acid amplification, a review

PJ Asiello, AJ Baeumner - Lab on a Chip, 2011 - pubs.rsc.org
Micro-Total Analysis Systems (µTAS) for use in on-site rapid detection of DNA or RNA are
increasingly being developed. Here, amplification of the target sequence is key to increasing …

Recent advances in microfluidics-based electrochemical sensors for foodborne pathogen detection

MB Kulkarni, NH Ayachit, TM Aminabhavi - Biosensors, 2023 - mdpi.com
Using pathogen-infected food that can be unhygienic can result in severe diseases and an
increase in mortality rate among humans. This may arise as a serious emergency problem if …

Isothermal amplification methods for the detection of nucleic acids in microfluidic devices

LM Zanoli, G Spoto - Biosensors, 2012 - mdpi.com
Diagnostic tools for biomolecular detection need to fulfill specific requirements in terms of
sensitivity, selectivity and high-throughput in order to widen their applicability and to …

Liquid–liquid phase separation in artificial cells

CD Crowe, CD Keating - Interface Focus, 2018 - royalsocietypublishing.org
Liquid–liquid phase separation (LLPS) in biology is a recently appreciated means of
intracellular compartmentalization. Because the mechanisms driving phase separations are …