Raman spectroscopy: an emerging tool in neurodegenerative disease research and diagnosis
G Devitt, K Howard, A Mudher… - ACS chemical …, 2018 - ACS Publications
The pathogenesis underlining many neurodegenerative diseases remains incompletely
understood. The lack of effective biomarkers and disease preventative medicine demands …
understood. The lack of effective biomarkers and disease preventative medicine demands …
Advances in Raman spectroscopy and imaging for biomedical research
Starting with a historical account of evolution in Raman spectroscopy, in this review we
provide details of the advancements that have pushed detection limits to single molecules …
provide details of the advancements that have pushed detection limits to single molecules …
Label-free imaging of amyloid plaques in Alzheimer's disease with stimulated Raman scattering microscopy
M Ji, M Arbel, L Zhang, CW Freudiger, SS Hou… - Science …, 2018 - science.org
One of the key pathological features of Alzheimer's disease (AD) is the existence of
extracellular deposition of amyloid plaques formed with misfolded amyloid-β (Aβ). The …
extracellular deposition of amyloid plaques formed with misfolded amyloid-β (Aβ). The …
Mechanisms of Biomolecular Self‐Assembly Investigated Through In Situ Observations of Structures and Dynamics
Biomolecular self‐assembly of hierarchical materials is a precise and adaptable bottom‐up
approach to synthesizing across scales with considerable energy, health, environment …
approach to synthesizing across scales with considerable energy, health, environment …
Rosmarinic acid prevents fibrillization and diminishes vibrational modes associated to β sheet in tau protein linked to Alzheimer's disease
A Cornejo, F Aguilar Sandoval… - Journal of enzyme …, 2017 - Taylor & Francis
Alzheimer's disease is a common tauopathy where fibril formation and aggregates are the
hallmark of the disease. Efforts targeting amyloid-β plaques have succeeded to remove …
hallmark of the disease. Efforts targeting amyloid-β plaques have succeeded to remove …
Three-dimensional ordered Ag/ZnO/Si hierarchical nanoflower arrays for spatially uniform and ultrasensitive SERS detection
Surface-enhanced Raman scattering (SERS) is a powerful analytic tool that can provide
information of molecular structures and composition of analytes. The application of SERS for …
information of molecular structures and composition of analytes. The application of SERS for …
Surface-enhanced Raman spectroscopy of tears: toward a diagnostic tool for neurodegenerative disease identification
G Cennamo, D Montorio, VB Morra… - … of biomedical optics, 2020 - spiedigitallibrary.org
Significance: A noninvasive method based on surface-enhanced Raman spectroscopy
(SERS) of tears was proposed as a support for diagnosing neurodegenerative pathologies …
(SERS) of tears was proposed as a support for diagnosing neurodegenerative pathologies …
Amyloidogenic proteins in the SARS-CoV and SARS-CoV-2 proteomes
The phenomenon of protein aggregation is associated with a wide range of human
diseases. Our knowledge of the aggregation behaviour of viral proteins, however, is still …
diseases. Our knowledge of the aggregation behaviour of viral proteins, however, is still …
Identification of amyloid beta in small extracellular vesicles via Raman spectroscopy
One of the hallmarks of Alzheimer's disease (AD) pathogenesis is believed to be the
production and deposition of amyloid-beta (Aβ) peptide into extracellular plaques. Existing …
production and deposition of amyloid-beta (Aβ) peptide into extracellular plaques. Existing …
Engaging with Raman spectroscopy to investigate antibody aggregation
I Ettah, L Ashton - Antibodies, 2018 - mdpi.com
In the last decade, a number of studies have successfully demonstrated Raman
spectroscopy as an emerging analytical technique for monitoring antibody aggregation …
spectroscopy as an emerging analytical technique for monitoring antibody aggregation …