Protein phosphorylation provides molecular control of complex physiological events within
cells. In many cases, phosphorylation on specific amino acids directly controls the assembly …

Caulobacter crescentus is an aquatic Gram-negative alphaproteobacterium that undergoes
multiple changes in cell shape, organelle production, subcellular distribution of proteins, and …

We report on a microfluidic particle-separation device that makes use of the asymmetric
bifurcation of laminar flow around obstacles. A particle chooses its path deterministically on …

Dividing cells must coordinate cell cycle events to ensure genetic stability. Here we identify
an essential two-component signal transduction protein that controls multiple events in the …

The chromosomal origin and terminus of replication are precisely localized in bacterial cells.
We examined the cellular position of 112 individual loci that are dispersed over the circular …

Second messengers control a wide range of important cellular functions in eukaryotes and
prokaryotes. Here we show that cyclic di-GMP, a global bacterial second messenger …

The global transcriptional regulator CtrA controls multiple events in the Caulobacter cell
cycle, including the initiation of DNA replication, DNA methylation, cell division, and flagellar …

Marine viruses impose a heavy mortality on their host bacteria, whereas at the same time the
degree of viral resistance in marine bacteria appears to be high. Antagonistic coevolution …

Achieving proper polarity is essential for cellular function. In bacteria, cell polarity has been
observed by using both morphological and molecular markers; however, no general …

Several members of the two‐component signal transduction family have been implicated in
the control of polar development in Caulobacter crescentus: PleC and DivJ, two polarly …