Diabetes mellitus is one of the biggest challenges for the scientific community in the 21st
century. It is a well-recognized multifactorial health problem contributes significantly to high …

The analogs of nitrogen-based heterocycles occupy an exclusive position as a valuable
source of therapeutic agents in medicinal chemistry. More than 75% of drugs approved by …

Abstract The 1, 2, 3-triazole ring is a major pharmacophore system among nitrogen-
containing heterocycles. These five-membered heterocyclic motifs with three nitrogen …

Due to the pharmacological activities of quinazoline and quinazolinone scaffolds, it has
aroused great interest in medicinal chemists for the development of new drugs or drug …

The review lays emphasis on the significance of 1, 2, 3-triazoles synthesized via CuAAC
reaction having potential to act as anti-microbial, anti-cancer, anti-viral, anti-inflammatory …

Diabetes is one of the major diseases worldwide and is the third leading cause of death in
the United States. Anti-diabetic drugs are used in the treatment of diabetes mellitus to control …

Abstract α-Glucosidase is a key enzyme in hydrolysis of carbohydrates to glucose and
located in the small intestine brush border. Inhibition of this enzyme delay the release of …

Background A large number of studies have recently reported that, because of their
significant biological and pharmacological properties, heterocyclic compounds and their …

Cancer is one of the leading causes of death globally, around 10 million deaths are reported
every year due to cancer. Some clinically approved anticancer drugs play a riveting role in …

Bacterial resistance remains a significant threat and a leading cause of death worldwide,
despite massive attempts to control infections. In an effort to develop biologically active …