Iron is a versatile redox-active catalyst and a required cofactor within a diverse array of
biological processes. To almost all organisms, iron is both essential and potentially toxic …

Staphylococcus aureus (S. aureus) infections are a major healthcare challenge and new
treatment alternatives are needed. S. aureus septic arthritis, a debilitating joint disease …

Release of extracellular vesicles (EVs) is a common feature among eukaryotes, archaea,
and bacteria. However, the biogenesis and downstream biological effects of EVs released …

Metals are common enzymatic cofactors, and their acquisition must be assured under the
various conditions encountered in the host. Although some strategies for acquisition of …

Nutritional immunity is a form of innate immunity widespread in both vertebrates and
invertebrates. The term refers to a rich repertoire of mechanisms set up by the host to inhibit …

Sepsis caused by Gram-positive bacterial pathogens is a major fatal disease but its
molecular basis remains elusive. Toll-like receptor 2 (TLR2) has been implicated in the …

In our previous study, several iron-related outer membrane proteins in Aeromonas
hydrophila, a serious pathogen of farmed fish, conferred high immunoprotectivity to fish, and …

Infections with the Gram-positive bacterial pathogen Staphylococcus aureus remain a major
challenge for the healthcare system and demand new treatment options. The increasing …

Staphylococcus xylosus belongs to the vast group of coagulase-negative staphylococci. It is
frequently isolated from meat products, either fermented or salted and dried, and is …

Iron (Fe) is a trace nutrient required by nearly all organisms. As a result of the demand for Fe
and the toxicity of non-chelated cytosolic ionic Fe, regulatory systems have evolved to tightly …