Insight into crosstalk between ferroptosis and necroptosis: novel therapeutics in ischemic stroke

Y Zhou, J Liao, Z Mei, X Liu, J Ge - Oxidative Medicine and …, 2021 - Wiley Online Library
Ferroptosis is a nonapoptotic form of cell death characterized by iron‐dependent
accumulation of lipid hydroperoxides to lethal levels. Necroptosis, an alternative form of …

[HTML][HTML] Necroptosis: a pathogenic negotiator in human diseases

HS Chaouhan, C Vinod, N Mahapatra, SH Yu… - International Journal of …, 2022 - mdpi.com
Over the past few decades, mechanisms of programmed cell death have attracted the
scientific community because they are involved in diverse human diseases. Initially …

Do pyroptosis, apoptosis, and necroptosis (PANoptosis) exist in cerebral ischemia? Evidence from cell and rodent studies

WT Yan, YD Yang, XM Hu, WY Ning… - Neural regeneration …, 2022 - journals.lww.com
Some scholars have recently developed the concept of PANoptosis in the study of infectious
diseases where pyroptosis, apoptosis and necroptosis act in consort in a multimeric protein …

Small extracellular vesicles secreted by human iPSC-derived MSC enhance angiogenesis through inhibiting STAT3-dependent autophagy in ischemic stroke

Y **a, X Ling, G Hu, Q Zhu, J Zhang, Q Li… - Stem cell research & …, 2020 - Springer
Background Small extracellular vesicles (sEV) secreted by mesenchymal stem cells (MSC)
derived from human induced pluripotent stem cells (iPSC, iMSC-sEV) are considered to …

The possible roles of necroptosis during cerebral ischemia and ischemia/reperfusion injury

S Liao, N Apaijai, N Chattipakorn… - Archives of Biochemistry …, 2020 - Elsevier
Cell death is a process consequential to cerebral ischemia and cerebral
ischemia/reperfusion (I/R) injury. Recent evidence suggest that necroptosis has been …

Novel insight into cGAS-STING pathway in ischemic stroke: from pre-to post-disease

X Ma, D **n, R She, D Liu, J Ge, Z Mei - Frontiers in immunology, 2023 - frontiersin.org
Ischemic stroke, a primary cause of disability and the second leading cause of mortality, has
emerged as an urgent public health issue. Growing evidence suggests that the Cyclic GMP …

RTN4/Nogo-A-S1PR2 negatively regulates angiogenesis and secondary neural repair through enhancing vascular autophagy in the thalamus after cerebral cortical …

P **ao, J Gu, W Xu, X Niu, J Zhang, J Li, Y Chen, Z Pei… - Autophagy, 2022 - Taylor & Francis
Cerebral infarction induces angiogenesis in the thalamus and influences functional
recovery. The mechanisms underlying angiogenesis remain unclear. This study aimed to …

Mitochondrial mechanisms of necroptosis in liver diseases

C Xue, X Gu, G Li, Z Bao, L Li - International Journal of Molecular …, 2020 - mdpi.com
Cell death represents a basic biological paradigm that governs outcomes and long-term
sequelae in almost every hepatic disease. Necroptosis is a common form of programmed …

MiR-211 protects cerebral ischemia/reperfusion injury by inhibiting cell apoptosis

W Liu, Y Miao, L Zhang, X Xu, Q Luan - Bioengineered, 2020 - Taylor & Francis
MicroRNAs (miRNAs) have emerged as critical regulators of neuronal survival during
cerebral ischemia/reperfusion injury. Accumulating evidence has shown that miR-211 plays …

[HTML][HTML] Melatonin modulates the aggravation of pyroptosis, necroptosis, and neuroinflammation following cerebral ischemia and reperfusion injury in obese rats

N Yawoot, J Sengking, P Govitrapong… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Obesity is well-established as a common comorbidity in ischemic stroke. The increasing
evidence has revealed that it also associates with the exacerbation of brain pathologies …