The recent commercialisation of the first disease-modifying drugs for Alzheimer's disease
emphasises the need for consensus recommendations on the rational use of biomarkers to …

The cerebral cortex has long been thought to be involved in the pathophysiology of motor
symptoms of Parkinson's disease. The impaired cortical function is believed to be a direct …

Background Enhanced glutamatergic transmission leading to motor neuron death is
considered the major pathophysiological mechanism of amyotrophic lateral sclerosis (ALS) …

Cortical hyperexcitability is an important pathophysiological mechanism in amyotrophic
lateral sclerosis (ALS), reflecting a complex interaction of inhibitory and facilitatory …

Specifically, the advent of cortical hyperexcitability has been consistently identified as an
early and intrinsic feature of ALS. With greater accessibility of TMS techniques promoting …

Alzheimer disease (AD) remains a significant global health concern. The progression from
preclinical stages to overt dementia has become a crucial point of interest for researchers …

Introduction Frontotemporal dementia (FTD) is a complex neurodegenerative disorder,
characterized by a wide range of pathological conditions associated with the buildup of …

Background Dysfunction in efferent pathways after knee pathology is tied to long-term
impairments in quadriceps and hamstrings muscle performance, daily function, and health …

Levodopa-induced dyskinesias (LIDs) are a common complication in patients with
Parkinson's disease (PD). A complex cascade of electrophysiological and molecular events …

Transcranial magnetic stimulation (TMS) methods have become exciting techniques for
altering brain activity and improving synaptic plasticity, earning recognition as valuable non …