Preparation and Post-Assembly Modification of Metallosupramolecular Assemblies from Poly(N-Heterocyclic Carbene) Ligands

MM Gan, JQ Liu, L Zhang, YY Wang, FE Hahn… - Chemical …, 2018 - ACS Publications
Although the coordination chemistry of N-heterocyclic carbenes (NHCs) with transition
metals has been explored for half a century, only in the past ten years has the chemistry of …

Update on metal N-heterocyclic carbene complexes as potential anti-tumor metallodrugs

W Liu, R Gust - Coordination Chemistry Reviews, 2016 - Elsevier
The clinical success of platinum-based chemotherapeutic agents was of enormous impact
on the discovery of novel metal N-heterocyclic carbene (NHC) complexes as potential anti …

Recent developments in the medicinal applications of silver-NHC complexes and imidazolium salts

NA Johnson, MR Southerland, WJ Youngs - Molecules, 2017 - mdpi.com
Because of their great structural diversity and multitude of chemical properties, N-
heterocyclic carbenes (NHCs) have been utilized in a variety of capacities. Most recently …

Silver (I) complexes of mono-and bidentate N-heterocyclic carbene ligands: Synthesis, crystal structures, and in vitro antibacterial and anticancer studies

RA Haque, SY Choo, S Budagumpi, MA Iqbal… - European journal of …, 2015 - Elsevier
A series of benzimidazole-based N-heterocyclic carbene (NHC) proligands {1-benzyl-3-(2-
methylbenzyl)-benzimidazolium bromide/hexafluorophosphate (1/4), 1, 3-bis (2 …

Biologically Relevant Silver (I)–N‐Heterocyclic Carbene Complexes: Synthesis, Structure, Intramolecular Interactions, and Applications

S Budagumpi, RA Haque, S Endud… - European Journal of …, 2013 - Wiley Online Library
N‐Heterocyclic carbenes (NHCs) complexed with silver represent new, broad‐spectrum
antimicrobial and anticancer agents, normally with low toxicity profiles, and they provide a …

Synthesis, Structure, and Anticancer Activity of Symmetrical and Non-symmetrical Silver(I)-N-Heterocyclic Carbene Complexes

M Atif, HN Bhatti, RA Haque, MA Iqbal… - Applied Biochemistry …, 2020 - Springer
Synthesis and anticancer studies of three symmetrically and non-symmetrically substituted
silver (I)-N-Heterocyclic carbene complexes of type [(NHC) 2-Ag] PF 6 (7–9) and their …

Potential of silver against human colon cancer: (synthesis, characterization and crystal structures of xylyl (Ortho, meta, & Para) linked bis-benzimidazolium salts and Ag(I)-NHC …

MA Iqbal, RA Haque, SF Nasri, AMSA Majid… - Chemistry Central …, 2013 - Springer
Background Since the first successful synthesis of Ag (I)-N-heterocyclic carbene complex in
1993, this class of compounds has been extensively used for transmetallation reactions …

Silver N‐heterocyclic carbene complexes bearing fluorinated benzyl group: Synthesis, characterization, crystal structure, computational studies, and inhibitory …

S Bal, Ö Demirci, B Şen, T Taşkın Tok… - Applied …, 2021 - Wiley Online Library
A series of the silver N‐heterocyclic carbene (NHC) complexes have been synthesized from
the reactions between benzimidazolium salts bearing fluorinated benzyl group and Ag2O …

Macrophage and colon tumor cells as targets for a binuclear silver (I) N-heterocyclic carbene complex, an anti-inflammatory and apoptosis mediator

MA Iqbal, MI Umar, RA Haque, MBK Ahamed… - Journal of inorganic …, 2015 - Elsevier
Chronic inflammation intensifies the risk for malignant neoplasm, indicating that curbing
inflammation could be a valid strategy to prevent or cure cancer. Cancer and inflammation …

In vitro and in silico anticancer potential of binuclear silver (I) N-heterocyclic carbene (NHCs) complexes: Investigation of interaction with surfactants

R Ashraf, S Akram, M El-Naggar, A Kanwal, TT Tok… - Inorganica Chimica …, 2024 - Elsevier
N-heterocyclic carbene (NHCs) silver complexes are getting tremendous attention for
appealing biological potentials. The present study is planned to synthesize silver-NHC …