One of the most prominent features of the human brain is the fabulous size of the cerebral
cortex and its intricate folding. Cortical folding takes place during embryonic development …

The relatively large brain and expanded cerebral cortex of humans is unusual in the animal
kingdom and is thought to have promoted our adaptability and success as a species. One …

Autosomal recessive primary microcephaly (MCPH) is a neurodevelopmental disorder that
is characterised by microcephaly present at birth and non-progressive mental retardation …

Genes associated with human microcephaly, a condition characterized by a small brain,
include critical regulators of proliferation, cell fate and DNA repair. We describe a syndrome …

Primary microcephaly (MCPH) is an autosomal-recessive congenital disorder characterized
by smaller-than-normal brain size and mental retardation. MCPH is genetically …

Primary microcephaly is a rare condition in which brain size is substantially diminished
without other syndromic abnormalities. Seven autosomal loci have been genetically …

Abstract Autosomal Recessive Primary Microcephaly (MCPH) is a rare disorder of
neurogenic mitosis characterized by reduced head circumference at birth with variable …

Autosomal recessive primary microcephaly (MCPH) is a rare hereditary
neurodevelopmental disorder characterized by a marked reduction in brain size and …

Autosomal recessive primary microcephaly (MCPH) is a neuro-developmental disorder that
causes a great reduction in brain growth in utero. MCPH is hypothesized to be a primary …

Background Mutations in the A bnormal Sp indle M icrocephaly related gene (ASPM) are the
commonest cause of autosomal recessive primary microcephaly (MCPH) a disorder …