Vascular dysfunction in Alzheimer's disease: a prelude to the pathological process or a consequence of it?

K Govindpani, LG McNamara, NR Smith… - Journal of clinical …, 2019 - mdpi.com
Alzheimer's disease (AD) is the most prevalent form of dementia. Despite decades of
research following several theoretical and clinical lines, all existing treatments for the …

[HTML][HTML] Therapy with voretigene neparvovec. How to measure success?

K Stingl, M Kempf, R Jung, F Kortuem, G Righetti… - Progress in Retinal and …, 2023 - Elsevier
Retinal gene supplementation therapy such as the first approved one, voretigene
neparvovec, delivers a functioning copy of the missing gene enabling the protein …

New noninvasive methods to evaluate microvascular structure and function

D Rizzoni, A Mengozzi, S Masi, C Agabiti Rosei… - …, 2022 - Am Heart Assoc
The structural and functional alterations of microvessels are detected because of
physiological aging and in several cardiometabolic diseases, including hypertension …

Imaging the retinal vasculature

SA Burns, AE Elsner, TJ Gast - Annual review of vision science, 2021 - annualreviews.org
Advances in retinal imaging are enabling researchers and clinicians to make precise
noninvasive measurements of the retinal vasculature in vivo. This includes measurements of …

Using artificial intelligence to analyse the retinal vascular network: the future of cardiovascular risk assessment based on oculomics? A narrative review

L Arnould, F Meriaudeau, C Guenancia… - Ophthalmology and …, 2023 - Springer
The healthcare burden of cardiovascular diseases remains a major issue worldwide.
Understanding the underlying mechanisms and improving identification of people with a …

[HTML][HTML] Adaptive optics ophthalmoscopy: a systematic review of vascular biomarkers

E Bakker, FA Dikland, R van Bakel, DA De Jesus… - Survey of …, 2022 - Elsevier
Retinal vascular diseases are a leading cause for blindness and partial sight certifications.
By applying adaptive optics (AO) to conventional imaging modalities, the microstructures of …

A literature review of hypertensive retinopathy: systemic correlations and new technologies

E Di Marco, F Aiello, M Lombardo… - European Review for …, 2022 - art.torvergata.it
OBJECTIVE: Hypertensive retinopathy (HR) is the most common ocular manifestation of
systemic arterial hypertension. This paper aims to summarize the current knowledge of HR …

Hypertension and the eye

L Konstantinidis, Y Guex-Crosier - Current opinion in …, 2016 - journals.lww.com
Assessment of hypertensive retinopathy signs may convey additional prognostic information
on the risk of end-organ damage and may alert for urgent systemic management or even …

Adaptive optics ophthalmoscopy: Application to age-related macular degeneration and vascular diseases

M Paques, S Meimon, F Rossant, D Rosenbaum… - Progress in retinal and …, 2018 - Elsevier
Adaptive optics (AO)-enhanced en face retinal imaging, termed here AO ophthalmoscopy
(AOO) has reached a level of robustness which fuels its increasing use in research and …

State of the art review: vascular remodeling in hypertension

D Rizzoni, C Agabiti-Rosei… - American Journal of …, 2023 - academic.oup.com
Although the gold-standard method for the assessment of structural alteration in small
resistance arteries is the evaluation of the MLR by micromyography in bioptic tissues, new …