Executive summary “Depression is a disorder of mood, so mysteriously painful and elusive
in the way it becomes known to the self—to the mediating intellect—as to verge close to …

Most mental disorders have a typical onset between 12 and 25 years of age, highlighting the
importance of this period for the pathogenesis, diagnosis, and treatment of mental ill-health …

Mental ill‐health represents the main threat to the health, survival and future potential of
young people around the world. There are indications that this is a rising tide of vulnerability …

Mental ill health, which has been the leading health and social issue impacting the lives and
futures of young people for decades, has entered a dangerous phase. Accumulating …

Executive summary The Sustainable Development Goals (SDGs) represent an exponential
advance from the Millennium Development Goals, with a substantially broader agenda …

Although mental health problems represent the largest burden of disease in young people,
access to mental health care has been poor for this group. Integrated youth health care …

Early intervention is a fundamental principle in health care and the past two decades have
seen it belatedly introduced into the field of mental health. This began in psychotic disorders …

Despite health gains over the past 30 years, children and adolescents are not reaching their
health potential in many low-income and middle-income countries (LMICs). In addition to …

Despite a lack of recent progress in the treatment of schizophrenia, our understanding of its
genetic and environmental causes has considerably improved, and their relationship to …

Background: The developmental period from 0 to 25 years is a vulnerable time during which
children and young people experience many psychosocial and neurobiological changes …