Identifying progression in multiple sclerosis: new perspectives

M Filippi, P Preziosa, D Langdon… - Annals of …, 2020 - Wiley Online Library
The identification of progression in multiple sclerosis is typically retrospective. Given the
profound burden of progressive multiple sclerosis, and the recent development of effective …

Disability outcome measures in phase III clinical trials in multiple sclerosis

BMJ Uitdehaag - CNS drugs, 2018 - Springer
Accumulating neurological disability has a substantial impact on the lives of patients with
multiple sclerosis (MS). As well as the established Expanded Disability Status Scale (EDSS) …

Validity and reliability of four clinical gait measures in patients with multiple sclerosis

SE Bennett, LE Bromley, NM Fisher… - … journal of MS care, 2017 - meridian.allenpress.com
Background: The gold standards for assessing ambulation are the Expanded Disability
Status Scale (EDSS) and the Timed 25-Foot Walk (T25FW) test. In relation with these …

Clinical and paraclinical biomarkers and the hitches to assess conversion to secondary progressive multiple sclerosis: a systematic review

N Krajnc, G Bsteh, T Berger - Frontiers in Neurology, 2021 - frontiersin.org
Conversion to secondary progressive (SP) course is the decisive factor for long-term
prognosis in relapsing multiple sclerosis (MS), generally considered the clinical equivalent …

Predictive MRI biomarkers in MS—A critical review

VE Tiu, I Enache, CA Panea, C Tiu, BO Popescu - Medicina, 2022 - mdpi.com
Background and Objectives: In this critical review, we explore the potential use of MRI
measurements as prognostic biomarkers in multiple sclerosis (MS) patients, for both …

'They're getting a taste of our world': A qualitative study of people with multiple sclerosis' experiences of accessing health care during the COVID‐19 pandemic in the …

A Parkinson, J Drew, S Hall Dykgraaf… - Health …, 2021 - Wiley Online Library
Background People with multiple sclerosis (MS), who are often immunocompromised,
require complex care and engage with a variety of health‐care providers to manage their …

Study for the validation of the FeetMe® integrated sensor insole system compared to GAITRite® system to assess gait characteristics in patients with multiple …

A Granja Domínguez, R Romero Sevilla, A Alemán… - Plos one, 2023 - journals.plos.org
Objective To determine the concordance and statistical precision in gait velocity in people
with multiple sclerosis (pwMS), measured with FeetMe®(insoles with pressure and motion …

Heart rate variability analysis in patients with multiple sclerosis

O Damla, C Altug, KK Pinar, K Alper, IG Dilek… - Multiple sclerosis and …, 2018 - Elsevier
Background Multiple sclerosis can cause cardiovascular autonomic dysfunction. It is
assumed that is caused by multiple demyelinating plaques localized in the brain stem and …

Correlation between the corpus callosum index and brain atrophy, lesion load, and cognitive dysfunction in multiple sclerosis

LI Gonçalves, GR Dos Passos, LP Conzatti… - Multiple sclerosis and …, 2018 - Elsevier
Background The corpus callosum index (CCI) can be easily and reliably obtained from
conventional magnetic resonance imaging (MRI) and has been proposed as a possible …

Emerging approaches for validating and managing multiple sclerosis relapse

EA Mills, A Mirza, Y Mao-Draayer - Frontiers in Neurology, 2017 - frontiersin.org
The autoimmune disease multiple sclerosis (MS) is characterized by relapses in the majority
of patients. A definitive clinical diagnosis of relapse in MS can be complicated by the …