Nanoscale mechanobiology of cell adhesions
Proper physiological functions of cells and tissues depend upon their abilities to sense,
transduce, integrate, and generate mechanical and biochemical signals. Although such …
transduce, integrate, and generate mechanical and biochemical signals. Although such …
Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions
Integrins are transmembrane receptors that, upon activation, bind extracellular ligands and
link them to the actin filament (F-actin) cytoskeleton to mediate cell adhesion and migration …
link them to the actin filament (F-actin) cytoskeleton to mediate cell adhesion and migration …
Mechanosensation: a catch bond that only hooks one way
Single-molecule force spectroscopy and modeling have revealed that the adhesion
molecule vinculin and F-actin form a catch bond that is dependent on the direction of forces …
molecule vinculin and F-actin form a catch bond that is dependent on the direction of forces …
Knockout and complementation of non-muscle α-actinin-1 and-4 reveals new aspects of their role in stress fiber formation, focal adhesion organization and cell …
A Timper - 2019 - kops.uni-konstanz.de
Knockout and complementation of non-muscle α-actinin-1 and -4 reveals new aspects of
their role in stress fiber formation, foca Page 1 Knockout and complementation of non-muscle …
their role in stress fiber formation, foca Page 1 Knockout and complementation of non-muscle …