Advances in ovarian cancer treatment beyond PARP inhibitors

F Aliyuda, M Moschetta, A Ghose… - Current cancer drug …, 2023 - benthamdirect.com
Ovarian cancer has become the largest cause of gynaecological cancer-related mortality. It
is typically diagnosed at a late stage and has no effective screening strategy. Ovarian cancer …

[HTML][HTML] Exosomes in the diagnosis and treatment of renal cell cancer

S Boussios, P Devo, ICA Goodall, K Sirlantzis… - International Journal of …, 2023 - mdpi.com
Renal cell carcinoma (RCC) is the most prevalent type of kidney cancer originating from
renal tubular epithelial cells, with clear cell RCC comprising approximately 80% of cases …

[HTML][HTML] Non-epithelial ovarian cancers: how much do we really know?

A Cheung, S Shah, J Parker, P Soor, A Limbu… - International journal of …, 2022 - mdpi.com
Non-epithelial ovarian cancers (NEOC) are a group of uncommon malignancies that mainly
includes germ cell tumours (GCT), sex cord-stromal tumours (SCST), and some extremely …

An overview of the role of MicroRNAs on carcinogenesis: a focus on cell cycle, angiogenesis and metastasis

L Pekarek, D Torres-Carranza… - International Journal of …, 2023 - mdpi.com
In recent years, the importance of epigenetic markers in the carcinogenesis of different
malignant neoplasms has been demonstrated, also demonstrating their utility for …

[HTML][HTML] Angiogenesis and anti-angiogenic treatment in prostate cancer: mechanisms of action and molecular targets

E Ioannidou, M Moschetta, S Shah, JS Parker… - International journal of …, 2021 - mdpi.com
Prostate cancer (PC) is the most common cancer in men and the second leading cause of
cancer-related death worldwide. Many therapeutic advances over the last two decades have …

Microsatellite instability testing in colorectal patients with Lynch syndrome: lessons learned from a case report and how to avoid such pitfalls

S Adeleke, A Haslam, A Choy, S Diaz-Cano… - Personalized …, 2022 - Taylor & Francis
We present the case of a patient with Lynch syndrome and metastatic colorectal carcinoma
(mCRC). The initial immunohistochemistry (IHC) test for deficient mismatch repair gave a …

Melanoma therapeutics: a literature review

PK Dhanyamraju, TN Patel - Journal of biomedical research, 2022 - pmc.ncbi.nlm.nih.gov
Melanoma is a relentless type of skin cancer which involves myriad signaling pathways
which regulate many cellular processes. This makes melanoma difficult to treat, especially …

Potential prognostic biomarkers of NIMA (Never in Mitosis, Gene A)-Related Kinase (NEK) family members in breast cancer

G Anuraga, WJ Wang, NN Phan, NT An Ton… - Journal of personalized …, 2021 - mdpi.com
Breast cancer remains the most common malignant cancer in women, with a staggering
incidence of two million cases annually worldwide; therefore, it is crucial to explore novel …

Advances in adoptive T-cell therapy for metastatic melanoma

A Das, A Ghose, K Naicker, E Sanchez… - Current research in …, 2023 - Elsevier
Adoptive T cell therapy (ACT) is a fast develo**, niche area of immunotherapy (IO), which
is revolutionising the therapeutic landscape of solid tumour oncology, especially metastatic …

[HTML][HTML] Hallmarks of the tumour microenvironment of gliomas and its interaction with emerging immunotherapy modalities

CA Linares, A Varghese, A Ghose, SD Shinde… - International Journal of …, 2023 - mdpi.com
Gliomas are aggressive, primary central nervous system tumours arising from glial cells.
Glioblastomas are the most malignant. They are known for their poor prognosis or median …