[HTML][HTML] The roles of Ca2+, downstream protein kinases, and oscillatory signaling in regulating fertilization and the activation of development

T Ducibella, R Fissore - Developmental biology, 2008 - Elsevier
Reviews in Developmental Biology have covered the pathways that generate the all-
important intracellular calcium (Ca2+) signal at fertilization [Miyazaki, S., Shirakawa, H …

Evolvable signaling networks of receptor tyrosine kinases: relevance of robustness to malignancy and to cancer therapy

I Amit, R Wides, Y Yarden - Molecular systems biology, 2007 - embopress.org
Robust biological signaling networks evolved, through gene duplications, from simple,
relatively fragile cascades. Architectural features such as layered configuration, branching …

Genomics and evolution of protein phosphatases

MJ Chen, JE Dixon, G Manning - Science signaling, 2017 - science.org
Protein phosphatases are the essential opposite to protein kinases; together, these enzymes
regulate all protein phosphorylation and most cellular processes. To better understand the …

Premetazoan genome evolution and the regulation of cell differentiation in the choanoflagellate Sal**oeca rosetta

SR Fairclough, Z Chen, E Kramer, Q Zeng, S Young… - Genome biology, 2013 - Springer
Background Metazoan multicellularity is rooted in mechanisms of cell adhesion, signaling,
and differentiation that first evolved in the progenitors of metazoans. To reconstruct the …

[HTML][HTML] The echinoderm adhesome

CA Whittaker, KF Bergeron, J Whittle… - Developmental …, 2006 - Elsevier
Although the development of sea urchin embryos has been studied extensively and clearly
involves both cell adhesion and cell migration, rather little is known about the adhesion …

Plk5, a polo box domain-only protein with specific roles in neuron differentiation and glioblastoma suppression

G de Cárcer, B Escobar, AM Higuero… - … and cellular biology, 2011 - Am Soc Microbiol
Polo-like kinases (Plks) are characterized by the presence of a specific domain, known as
the polo box (PBD), involved in protein-protein interactions. Plk1 to Plk4 are involved in …

The Src module: an ancient scaffold in the evolution of cytoplasmic tyrosine kinases

NH Shah, JF Amacher, LM Nocka… - Critical reviews in …, 2018 - Taylor & Francis
Tyrosine kinases were first discovered as the protein products of viral oncogenes. We now
know that this large family of metazoan enzymes includes nearly one hundred structurally …

Integrated characterization and risk management of marine sediments: The case study of the industrialized Bagnoli area (Naples, Italy)

L Morroni, G d'Errico, M Sacchi, F Molisso… - Marine environmental …, 2020 - Elsevier
The aim of the present work is to demonstrate the practical importance of a multidisciplinary
approach and weighted criteria to synthesize and integrate different typologies of data (or …

Protein phosphorylation database and prediction tools

MX Zhao, Q Chen, F Li, S Fu, B Huang… - Briefings in …, 2023 - academic.oup.com
Protein phosphorylation, one of the main protein post-translational modifications, is required
for regulating various life activities. Kinases and phosphatases that regulate protein …

The SH2 domain–containing proteins in 21 species establish the provenance and scope of phosphotyrosine signaling in eukaryotes

BA Liu, E Shah, K Jablonowski, A Stergachis… - Science …, 2011 - science.org
The Src homology 2 (SH2) domains are participants in metazoan signal transduction, acting
as primary mediators for regulated protein-protein interactions with tyrosine-phosphorylated …