Background Cerebral small vessel disease (cSVD) is a major contributing factor to ischemic
stroke and dementia. However, the vascular pathologies of cSVD remain inconclusive. The …

Cerebral small vessel disease (CSVD) results in a spectrum of neurologic, behavioral, and
cognitive sequelae, most commonly from white matter hyperintensities (WMH) of presumed …

Background Within the spectrum of Lewy body disorders (LBD), both Parkinson's disease
(PD) and dementia with Lewy bodies (DLB) are characterized by gait and balance …

Background Perivascular spaces on brain magnetic resonance imaging (MRI) may indicate
poor fluid drainage in the brain and have been associated with numerous neurological …

Cerebrovascular reactivity (CVR) deficits may contribute to small vessel disease, such as
white matter hyperintensities (WMH). Moreover, apolipoprotein-e4 (APOE4) carriers at …

Background: Cerebral amyloid angiopathy (CAA) is associated with cognitive decline. CAA
has diverse impacts on brain structure and function; however, the brain lesions that mediate …

Background Alzheimer's disease (AD) is a common, progressive, irreversible, and fatal
neurodegenerative disorder with rapidly increasing worldwide incidence. Although much …

Background and Objectives Cerebral small vessel disease (cSVD) is a major cause of stroke
and dementia, but little is known about disease mechanisms at the level of the small vessels …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by
memory impairment and cognitive decline, ultimately culminating in dementia. This study …

Background Parkinson's disease (PD) and dementia with Lewy bodies (DLB) are part of a
spectrum of Lewy body disorders, who exhibit a range of cognitive and gait impairments …