Current cancer immunotherapies are primarily predicated on αβ T cells, with a stringent
dependence on MHC-mediated presentation of tumour-enriched peptides or unique …

The intricacy of diseases, shaped by intrinsic processes like immune system exhaustion and
hyperactivation, highlights the potential of immune renormalization as a promising strategy …

Abstract γδ T cells are a unique T cell subpopulation that are rare in secondary lymphoid
organs but enriched in many peripheral tissues, such as the skin, intestines and lungs. By …

γδ T-cells directly recognize and kill transformed cells independently of HLA-antigen
presentation, which makes them a highly promising effector cell compartment for cancer …

Abstract γδ T cells are potent anticancer effectors with the potential to target tumours
broadly, independent of patient-specific neoantigens or human leukocyte antigen …

As a nontraditional T-cell subgroup, γδT cells have gained popularity in the field of
immunotherapy in recent years. They have extraordinary antitumor potential and prospects …

In both cancer and infections, diseased cells are presented to human Vγ9Vδ2 T cells
through an 'inside out'signalling process whereby structurally diverse phosphoantigen (pAg) …

Spillover events of avian influenza A viruses (IAVs) to humans could represent the first step
in a future pandemic. Several factors that limit the transmission and replication of avian IAVs …

Clinical responses to checkpoint inhibitors used for cancer immunotherapy seemingly
require the presence of αβT cells that recognize tumour neoantigens, and are therefore …

Abstract γδ T cells play uniquely important roles in stress surveillance and immunity for
infections and carcinogenesis. Human γδ T cells recognize and kill transformed cells …