Systematic review and meta-analysis of the magnitude of structural, clinical, and physician and patient barriers to cancer clinical trial participation
Background Barriers to cancer clinical trial participation have been the subject of frequent
study, but the rate of trial participation has not changed substantially over time. Studies often …
study, but the rate of trial participation has not changed substantially over time. Studies often …
Enrollment of racial minorities in clinical trials: old problem assumes new urgency in the age of immunotherapy.
Minority US populations are underrepresented in cancer clinical trials. This review appraises
the impact of the disparity in clinical trial participation by minority patients in the current era …
the impact of the disparity in clinical trial participation by minority patients in the current era …
Representation and extrapolation: evidence from clinical trials
This article examines the consequences and causes of low enrollment of Black patients in
clinical trials. We develop a simple model of similarity-based extrapolation that predicts that …
clinical trials. We develop a simple model of similarity-based extrapolation that predicts that …
Industry involvement and transparency in the most cited clinical trials, 2019-2022
Importance Industry involvement is prominent in influential clinical trials, and commitments to
transparency of trials are highly variable. Objective To evaluate the modes of industry …
transparency of trials are highly variable. Objective To evaluate the modes of industry …
Patient and public involvement in the design of clinical trials: an overview of systematic reviews
Background Funders encourage lay‐volunteer inclusion in research. There are controversy
and resistance, given concerns of role confusion, exploratory methods, and limited evidence …
and resistance, given concerns of role confusion, exploratory methods, and limited evidence …
A comprehensive review of randomized clinical trials in three medical journals reveals 396 medical reversals
D Herrera-Perez, A Haslam, T Crain, J Gill… - Elife, 2019 - elifesciences.org
The ability to identify medical reversals and other low-value medical practices is an essential
prerequisite for efforts to reduce spending on such practices. Through an analysis of more …
prerequisite for efforts to reduce spending on such practices. Through an analysis of more …
Diversity of enrollment in prostate cancer clinical trials: current status and future directions
Background: Although there are considerable racial and ethnic disparities in prostate cancer
incidence and mortality in the United States and globally, clinical trials often do not reflect …
incidence and mortality in the United States and globally, clinical trials often do not reflect …
Consent document translation expense hinders inclusive clinical trial enrolment
MA Velez, BA Glenn, M Garcia-Jimenez, AL Cummings… - Nature, 2023 - nature.com
Patients from historically under-represented racial and ethnic groups are enrolled in cancer
clinical trials at disproportionately low rates in the USA,–. As these patients often have …
clinical trials at disproportionately low rates in the USA,–. As these patients often have …
The promises and pitfalls of sex difference research
Abstract Funding agencies in North America and Europe are recognizing the importance of
the integration of sex differences into basic and clinical research. Although these mandates …
the integration of sex differences into basic and clinical research. Although these mandates …
[HTML][HTML] Metrics, baseline scores, and a tool to improve sponsor performance on clinical trial diversity: retrospective cross sectional study
Metrics, baseline scores, and a tool to improve sponsor performance on clinical trial diversity:
retrospective cross sectional study - PMC Back to Top Skip to main content NIH NLM Logo …
retrospective cross sectional study - PMC Back to Top Skip to main content NIH NLM Logo …