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[HTML][HTML] Oriented immobilization of antibodies onto sensing platforms-A critical review
The immunosensor has been proven a versatile tool to detect various analytes, such as food
contaminants, pathogenic bacteria, antibiotics and biomarkers related to cancer. To fabricate …
contaminants, pathogenic bacteria, antibiotics and biomarkers related to cancer. To fabricate …
Considerations for the design of antibody-based therapeutics
Antibody-based proteins have become an important class of biologic therapeutics, due in
large part to the stability, specificity, and adaptability of the antibody framework. Indeed …
large part to the stability, specificity, and adaptability of the antibody framework. Indeed …
Gold Nanoparticle-Coated Starch Magnetic Beads for the Separation, Concentration, and SERS-Based Detection of E. coli O157:H7
Here, we report gold nanoparticle-coated starch magnetic beads (AuNP@ SMBs) that were
prepared by in situ synthesis of AuNPs on the surface of SMBs. Upon functionalization of the …
prepared by in situ synthesis of AuNPs on the surface of SMBs. Upon functionalization of the …
Recent advances in lipid nanoparticles for delivery of nucleic acid, mRNA, and gene editing-based therapeutics
H Mukai, K Ogawa, N Kato, S Kawakami - Drug metabolism and …, 2022 - Elsevier
Lipid nanoparticles (LNPs) are becoming popular as a means of delivering therapeutics,
including those based on nucleic acids and mRNA. The mRNA-based coronavirus disease …
including those based on nucleic acids and mRNA. The mRNA-based coronavirus disease …
Determination of the protein content of complex samples by aromatic amino acid analysis, liquid chromatography-UV absorbance, and colorimetry
Fast and accurate determination of the protein content of a sample is an important and non-
trivial task of many biochemical, biomedical, food chemical, pharmaceutical, and …
trivial task of many biochemical, biomedical, food chemical, pharmaceutical, and …
[HTML][HTML] Biofunctionalization of multiplexed silicon photonic biosensors
Silicon photonic (SiP) sensors offer a promising platform for robust and low-cost
decentralized diagnostics due to their high scalability, low limit of detection, and ability to …
decentralized diagnostics due to their high scalability, low limit of detection, and ability to …
AJICAP: affinity peptide mediated regiodivergent functionalization of native antibodies
K Yamada, N Shikida, K Shimbo, Y Ito… - Angewandte …, 2019 - Wiley Online Library
The need for atom‐precise biomolecule modification, and particularly the irreversible
formation of covalent bonds to specific amino acids in proteins, has become an essential …
formation of covalent bonds to specific amino acids in proteins, has become an essential …
Immunoglobulin G structure and rheumatoid factor epitopes
SL Maibom-Thomsen, NH Trier, BE Holm, KB Hansen… - PLoS …, 2019 - journals.plos.org
Antibodies are important for immunity and exist in several classes (IgM, IgD, IgA, IgG, IgE).
They are composed of symmetric dimeric molecules with two antigen binding regions (Fab) …
They are composed of symmetric dimeric molecules with two antigen binding regions (Fab) …
Label-free immunodetection of α-synuclein by using a microfluidics coplanar electrolyte-gated organic field-effect transistor
The aggregation of α-synuclein is a critical event in the pathogenesis of neurological
diseases, such as Parkinson or Alzheimer. Here, we present a label-free sensor based on …
diseases, such as Parkinson or Alzheimer. Here, we present a label-free sensor based on …
Genetically encoded self-assembling protein nanoparticles for the targeted delivery in vitro and in vivo
Targeted nanoparticles of different origins are considered as new-generation diagnostic and
therapeutic tools. However, there are no targeted drug formulations within the composition of …
therapeutic tools. However, there are no targeted drug formulations within the composition of …