Imaging Biomarkers in Prodromal and Earliest Phases of Parkinson's Disease

H Theis, N Pavese, I Rektorová… - Journal of Parkinson's …, 2024 - content.iospress.com
Assessing imaging biomarker in the prodromal and early phases of Parkinson's disease
(PD) is of great importance to ensure an early and safe diagnosis. In the last decades …

Behavioral disorders in Parkinson disease: current view

KA Jellinger - Journal of Neural Transmission, 2024 - Springer
Patients with Parkinson disease (PD) frequently experience several behavioral symptoms,
such as anxiety, apathy, irritability, agitation, impulsive control and obsessive–compulsive or …

Longitudinal network changes and phenoconversion risk in isolated REM sleep behavior disorder

CC Tang, Y Nakano, A Vo, N Nguyen… - Nature …, 2024 - nature.com
Isolated rapid eye movement sleep behavior disorder is a prodrome of α-synucleinopathies.
Using positron emission tomography, we assessed changes in Parkinson's disease-related …

Network disruption based on multi-modal EEG-MRI in α-synucleinopathies

C Wang, J Hu, P Li, M Zhang, L Zhou, N Luo… - Frontiers in …, 2024 - frontiersin.org
Background Brain network dysfunction has been characterized by resting-state
electroencephalography (EEG) and magnetic resonance imaging (MRI) in the prodromal …

Investigating the aspect of asymmetry in brain-first versus body-first Parkinson's disease

SS Lövdal, G Carli, B Orso, M Biehl, D Arnaldi… - npj Parkinson's …, 2024 - nature.com
Parkinson's disease (PD) is characterized by a progressive loss of dopaminergic neurons in
the substantia nigra. Recent literature has proposed two subgroups of PD. The “body-first …

Individual‐specific metabolic network based on 18F‐FDG PET revealing multi‐level aberrant metabolisms in Parkinson's disease

W Lu, T Song, J Li, Y Zhang, J Lu - Human Brain Map**, 2024 - Wiley Online Library
Metabolic network analysis in Parkinson's disease (PD) based on 18F‐FDG PET has
revealed PD‐related metabolic patterns. However, alterations at the systemic metabolic …

Longitudinal Network Changes and Phenoconversion Risk in Isolated REM Sleep Behavior Disorder

D Eidelberg, C Tang, Y Nakano, A Vo, N Nguyen… - 2024 - researchsquare.com
Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal syndrome for
Parkinson's disease (PD) and related 𝛼-synucleinopathies. We conducted a longitudinal …

Altered Intra‐and Inter‐Network Resting‐State Functional Connectivity is Associated with Neuropsychological Functioning and Clinical Symptoms in Patients with …

I Roura, J Pardo, C Martín‐Barceló, J Oltra… - Movement … - Wiley Online Library
Background Isolated rapid‐eye movement (REM) sleep behavior disorder (iRBD) is
characterized by abnormal behaviors in REM sleep and is considered as a prodromal …

The combination of the 18F-FDG and 18F-FP-DTBZ PET for early diagnosis of cerebral glucose metabolism and dopaminergic dysfunction in Parkinson's disease

J Lu, WZ Lu, TB Song, C Zhang, C Yang - 2024 - researchsquare.com
Objective: This study aimed to use 18 F-FDG and 18 F-FP-DTBZ PET to illustrate the
correlation between cerebral glucose metabolism and nigrostriatal dopamine function and to …

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