The tectum/superior colliculus as the vertebrate solution for spatial sensory integration and action
The superior colliculus, or tectum in the case of non-mammalian vertebrates, is a part of the
brain that registers events in the surrounding space, often through vision and hearing, but …
brain that registers events in the surrounding space, often through vision and hearing, but …
The nature and neurobiology of fear and anxiety: State of the science and opportunities for accelerating discovery
Fear and anxiety play a central role in mammalian life, and there is considerable interest in
clarifying their nature, identifying their biological underpinnings, and determining their …
clarifying their nature, identifying their biological underpinnings, and determining their …
AAV-mediated anterograde transsynaptic tagging: map** corticocollicular input-defined neural pathways for defense behaviors
To decipher neural circuits underlying brain functions, viral tracers are widely applied to map
input and output connectivity of neuronal populations. Despite the successful application of …
input and output connectivity of neuronal populations. Despite the successful application of …
A synaptic threshold mechanism for computing escape decisions
Esca** from imminent danger is an instinctive behaviour that is fundamental for survival,
and requires the classification of sensory stimuli as harmless or threatening. The absence of …
and requires the classification of sensory stimuli as harmless or threatening. The absence of …
Feature detection by retinal ganglion cells
D Kerschensteiner - Annual review of vision science, 2022 - annualreviews.org
Retinal circuits transform the pixel representation of photoreceptors into the feature
representations of ganglion cells, whose axons transmit these representations to the brain …
representations of ganglion cells, whose axons transmit these representations to the brain …
Organization of the inputs and outputs of the mouse superior colliculus
NL Benavidez, MS Bienkowski, M Zhu… - Nature …, 2021 - nature.com
The superior colliculus (SC) receives diverse and robust cortical inputs to drive a range of
cognitive and sensorimotor behaviors. However, it remains unclear how descending cortical …
cognitive and sensorimotor behaviors. However, it remains unclear how descending cortical …
Defensive responses: Behaviour, the brain and the body
YT Tseng, B Schaefke, P Wei, L Wang - Nature Reviews Neuroscience, 2023 - nature.com
Most animals live under constant threat from predators, and predation has been a major
selective force in sha** animal behaviour. Nevertheless, defence responses against …
selective force in sha** animal behaviour. Nevertheless, defence responses against …
Vision guides selection of freeze or flight defense strategies in mice
G De Franceschi, T Vivattanasarn, AB Saleem… - Current biology, 2016 - cell.com
In prey species such as mice, avoidance of predators is key to survival and drives instinctual
behaviors like freeze or flight [1, 2]. Sensory signals guide the selection of appropriate …
behaviors like freeze or flight [1, 2]. Sensory signals guide the selection of appropriate …
Architecture, function, and assembly of the mouse visual system
TA Seabrook, TJ Burbridge, MC Crair… - Annual review of …, 2017 - annualreviews.org
Vision is the sense humans rely on most to navigate the world, make decisions, and perform
complex tasks. Understanding how humans see thus represents one of the most …
complex tasks. Understanding how humans see thus represents one of the most …
[HTML][HTML] A central alarm system that gates multi-sensory innate threat cues to the amygdala
Perception of threats is essential for survival. Previous findings suggest that parallel
pathways independently relay innate threat signals from different sensory modalities to …
pathways independently relay innate threat signals from different sensory modalities to …