Emerging role of exosomes in cancer progression and tumor microenvironment remodeling

MDA Paskeh, M Entezari, S Mirzaei, A Zabolian… - Journal of hematology & …, 2022 - Springer
Cancer is one of the leading causes of death worldwide, and the factors responsible for its
progression need to be elucidated. Exosomes are structures with an average size of 100 nm …

The role and regulation of integrins in cell migration and invasion

MR Chastney, J Kaivola, VM Leppänen… - … Reviews Molecular Cell …, 2025 - nature.com
Integrin receptors are the main molecular link between cells and the extracellular matrix
(ECM) as well as mediating cell–cell interactions. Integrin–ECM binding triggers the …

[HTML][HTML] Insight into extracellular vesicle-cell communication: from cell recognition to intracellular fate

L Ginini, S Billan, E Fridman, Z Gil - Cells, 2022 - mdpi.com
Extracellular vesicles (EVs) are heterogamous lipid bilayer-enclosed membranous
structures secreted by cells. They are comprised of apoptotic bodies, microvesicles, and …

Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy

CP Vellano, MG White, MC Andrews, M Chelvanambi… - Nature, 2022 - nature.com
Abstract Treatment with therapy targeting BRAF and MEK (BRAF/MEK) has revolutionized
care in melanoma and other cancers; however, therapeutic resistance is common and …

Emerging role of exosomes as biomarkers in cancer treatment and diagnosis

NA Hanjani, N Esmaelizad, S Zanganeh… - Critical reviews in …, 2022 - Elsevier
Cancer is a leading cause of death worldwide and cancer incidence and mortality are
rapidly growing. These massive amounts of cancer patients require rapid diagnosis and …

Role of exosomes in prostate cancer metastasis

T Akoto, S Saini - International journal of molecular sciences, 2021 - mdpi.com
Prostate cancer remains a life-threatening disease among men worldwide. The majority of
PCa-related mortality results from metastatic disease that is characterized by metastasis of …

Updates on liquid biopsy: Current trends and future perspectives for clinical application in solid tumors

P Pinzani, V D'Argenio, M Del Re… - Clinical Chemistry and …, 2021 - degruyter.com
Despite advances in screening and therapeutics cancer continues to be one of the major
causes of morbidity and mortality worldwide. The molecular profile of tumor is routinely …

[HTML][HTML] Extracellular vesicle-embedded materials

Y Ma, S Brocchini, GR Williams - Journal of Controlled Release, 2023 - Elsevier
Extracellular vesicles (EVs) are small membrane-bound vesicles released by cells. EVs are
emerging as a promising class of therapeutic entity that could be adapted in formulation due …

Prostate cancer-derived small extracellular vesicle proteins: the hope in diagnosis, prognosis, and therapeutics

H Chen, B Pang, C Zhou, M Han, J Gong, Y Li… - Journal of …, 2023 - Springer
Current diagnostic tools for prostate cancer (PCa) diagnosis and risk stratification are
insufficient. The hidden onset and poor efficacy of traditional therapies against metastatic …

Vasculature organotropism in drug delivery

A Amruta, D Iannotta, SW Cheetham, T Lammers… - Advanced drug delivery …, 2023 - Elsevier
Over the past decades, there has been an exponential increase in the development of
preclinical and clinical nanodelivery systems, and recently, an accelerating demand to …