Staphylococcal biofilm development: structure, regulation, and treatment strategies
K Schilcher, AR Horswill - Microbiology and Molecular Biology …, 2020 - Am Soc Microbiol
In many natural and clinical settings, bacteria are associated with some type of biotic or
abiotic surface that enables them to form biofilms, a multicellular lifestyle with bacteria …
abiotic surface that enables them to form biofilms, a multicellular lifestyle with bacteria …
Regulation of Staphylococcus aureus Virulence
Staphylococcus aureus is a Gram-positive opportunistic pathogen that has evolved a
complex regulatory network to control virulence. One of the main functions of this …
complex regulatory network to control virulence. One of the main functions of this …
A Review of Biofilm Formation of Staphylococcus aureus and Its Regulation Mechanism
Q Peng, X Tang, W Dong, N Sun, W Yuan - Antibiotics, 2022 - mdpi.com
Bacteria can form biofilms in natural and clinical environments on both biotic and abiotic
surfaces. The bacterial aggregates embedded in biofilms are formed by their own produced …
surfaces. The bacterial aggregates embedded in biofilms are formed by their own produced …
Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …
Staphylococcus aureus bloodstream infections: pathogenesis and regulatory mechanisms
Highlights•Phagocytes play both protective and detrimental roles in containing bloodstream
S. aureus.•S. aureus hijacks the host coagulation system and uses it to bind host …
S. aureus.•S. aureus hijacks the host coagulation system and uses it to bind host …
S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis
L Deng, F Costa, KJ Blake, S Choi, A Chandrabalan… - Cell, 2023 - cell.com
Itch is an unpleasant sensation that evokes a desire to scratch. The skin barrier is constantly
exposed to microbes and their products. However, the role of microbes in itch generation is …
exposed to microbes and their products. However, the role of microbes in itch generation is …
Bloodstream infections: mechanisms of pathogenesis and opportunities for intervention
CL Holmes, OR Albin, HLT Mobley… - Nature Reviews …, 2024 - nature.com
Bloodstream infections (BSIs) are common in hospitals, often life-threatening and increasing
in prevalence. Microorganisms in the blood are usually rapidly cleared by the immune …
in prevalence. Microorganisms in the blood are usually rapidly cleared by the immune …
Staphylococcus aureus cell wall maintenance – the multifaceted roles of peptidoglycan hydrolases in bacterial growth, fitness, and virulence
M Wang, G Buist, JM van Dijl - FEMS microbiology reviews, 2022 - academic.oup.com
Staphylococcus aureus is an important human and livestock pathogen that is well-protected
against environmental insults by a thick cell wall. Accordingly, the wall is a major target of …
against environmental insults by a thick cell wall. Accordingly, the wall is a major target of …
Thinking outside the box—novel antibacterials to tackle the resistance crisis
M Lakemeyer, W Zhao, FA Mandl… - Angewandte Chemie …, 2018 - Wiley Online Library
The public view on antibiotics as reliable medicines changed when reports about “resistant
superbugs” appeared in the news. While reasons for this resistance development are easily …
superbugs” appeared in the news. While reasons for this resistance development are easily …
Staphylococcus aureus RNAIII and Its Regulon Link Quorum Sensing, Stress Responses, Metabolic Adaptation, and Regulation of Virulence Gene Expression
Staphylococcus aureus RNAIII is one of the main intracellular effectors of the quorum-
sensing system. It is a multifunctional RNA that encodes a small peptide, and its noncoding …
sensing system. It is a multifunctional RNA that encodes a small peptide, and its noncoding …