[HTML][HTML] The role of lipids in pulmonary surfactant
Pulmonary surfactant is composed of approx. 90% lipids and 10% protein. This review
article focusses on the lipid components of surfactant. The first sections will describe the lipid …
article focusses on the lipid components of surfactant. The first sections will describe the lipid …
Pulmonary surfactant: a mighty thin film
Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …
[HTML][HTML] Current perspectives in pulmonary surfactant—inhibition, enhancement and evaluation
Pulmonary surfactant (PS) is a complicated mixture of approximately 90% lipids and 10%
proteins. It plays an important role in maintaining normal respiratory mechanics by reducing …
proteins. It plays an important role in maintaining normal respiratory mechanics by reducing …
[HTML][HTML] Structure of pulmonary surfactant membranes and films: the role of proteins and lipid–protein interactions
J Pérez-Gil - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2008 - Elsevier
The pulmonary surfactant system constitutes an excellent example of how dynamic
membrane polymorphism governs some biological functions through specific lipid–lipid …
membrane polymorphism governs some biological functions through specific lipid–lipid …
Surfactant-associated proteins: functions and structural variation
HP Haagsman, RV Diemel - … Biochemistry and Physiology Part A: Molecular …, 2001 - Elsevier
Pulmonary surfactant is a barrier material of the lungs and has a dual role: firstly, as a true
surfactant, lowering the surface tension; and secondly, participating in innate immune …
surfactant, lowering the surface tension; and secondly, participating in innate immune …
[HTML][HTML] Formation and structure of surface films: captive bubble surfactometry
S Schürch, FHY Green, H Bachofen - Biochimica et Biophysica Acta (BBA) …, 1998 - Elsevier
The adsorption model for soluble surfactants has been modified for suspensions of
pulmonary surfactant. The dynamic adsorption behavior may be governed by a two-step …
pulmonary surfactant. The dynamic adsorption behavior may be governed by a two-step …
[HTML][HTML] Advances in the characterization of supported lipid films with the atomic force microscope
During the past decade, the atomic force microscope (AFM) has become a key technique in
biochemistry and biophysics to characterize supported lipid films, as testified by the …
biochemistry and biophysics to characterize supported lipid films, as testified by the …
Pulmonary surfactant and drug delivery: Vehiculization, release and targeting of surfactant/tacrolimus formulations
This work explores the potential for strategizing pulmonary surfactant (PS) for drug delivery
over the respiratory air-liquid interface: the interfacial delivery. The efficacy of PS-and …
over the respiratory air-liquid interface: the interfacial delivery. The efficacy of PS-and …
[HTML][HTML] Role of lipid ordered/disordered phase coexistence in pulmonary surfactant function
C Casals, O Cañadas - Biochimica et Biophysica Acta (BBA) …, 2012 - Elsevier
The respiratory epithelium has evolved to produce a complicated network of extracellular
membranes that are essential for breathing and, ultimately, survival. Surfactant membranes …
membranes that are essential for breathing and, ultimately, survival. Surfactant membranes …
Synthetic surfactants with SP‐B and SP‐C analogues to enable worldwide treatment of neonatal respiratory distress syndrome and other lung diseases
J Johansson, T Curstedt - Journal of internal medicine, 2019 - Wiley Online Library
Abstract Treatment of neonatal respiratory distress syndrome (RDS) using animal‐derived
lung surfactant preparations has reduced the mortality of handling premature infants with …
lung surfactant preparations has reduced the mortality of handling premature infants with …