Background In patients with ischemic stroke, endovascular treatment results in a higher rate
of recanalization of the affected cerebral artery than systemic intravenous thrombolytic …

Worldwide, stroke is a leading cause of death and disability. Recombinant tissue
plasminogen activator (rtPA) was approved a decade ago for the treatment of acute ischemic …

Background and Purpose—The authors present an overview of the current evidence and
management recommendations for evaluation and treatment of adults with acute ischemic …

Importance It is estimated that only 27% of patients with acute ischemic stroke and large
vessel occlusion who undergo successful reperfusion after mechanical thrombectomy are …

This article represents the update of the European Stroke Initiative Recommendations for
Stroke Management. These guidelines cover both ischaemic stroke and transient ischaemic …

This article represents the update of the European Stroke Initiative Recommendations for
Stroke Management. These guidelines cover both ischaemic stroke and transient ischaemic …

BACKGROUND AND PURPOSE: Clot extent, location, and collateral integrity are important
determinants of outcome in acute stroke. We hypothesized that a novel clot burden score …

Background and Purpose—The purpose of this study was to provide the first correlative
study of the hyperdense middle cerebral artery sign (HMCAS) and gradient-echo MRI …

PURPOSE: The reported outcomes of central retinal artery occlusion (CRAO) with or without
treatment vary considerably. Although local intra-arterial fibrinolysis (LIF) using recombinant …

Background The efficacy of intravenous (IV) alteplase is restricted by the speed of
recanalisation and the site of the occlusion. The aim of this study was to ascertain the effect …