Peroxiredoxins (Prxs) constitute a major family of peroxidases, with mammalian cells
expressing six Prx isoforms (PrxI to PrxVI). Cells produce hydrogen peroxide (H2O2) at …

Peroxiredoxins (PRDXs) are antioxidant enzymes, known to catalyze peroxide reduction to
balance cellular hydrogen peroxide (H 2 O 2) levels, which are essential for cell signaling …

Background: Pathological cardiac hypertrophy is one of the leading causes of heart failure
with highly complicated pathogeneses. The E3 ligase TRIM16 (tripartite motif–containing …

Peroxiredoxins (Prdxs) sense and assess peroxide levels, and signal through protein
interactions. Understanding the role of the multiple structural and post-translational …

Peroxiredoxins are central to cellular redox homeostasis and signaling. They serve as
peroxide scavengers, sensors, signal transducers, and chaperones, depending on …

Advanced paternal age is linked to complications in pregnancy and genetic diseases in
offspring. Aging results in excess reactive oxygen species (ROS) and DNA damage in …

Objective To date, it is unclear whether deltamethrin (DLM) intake causes damage to colon
tissue. Hence, in this study, we aimed to clarify the effect of long-term exposure to low-dose …

Premature senescence of renal tubular epithelial cell (RTEC), which is involved in kidney
fibrosis, is a key event in the progression of diabetic nephropathy. However, the underlying …

Significance: Oxidative stress is a common feature of autoimmune diseases. Low levels of
reactive oxygen species (ROS) generation are important for various biological processes …

Degenerative suspensory ligament desmitis is a progressive idiopathic condition that leads
to scarring and rupture of suspensory ligament fibers in multiple limbs in horses. The …