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Metabolomics in infectious diseases and drug discovery
Metabolomics has emerged as an invaluable tool that can be used along with genomics,
transcriptomics and proteomics to understand host–pathogen interactions at small-molecule …
transcriptomics and proteomics to understand host–pathogen interactions at small-molecule …
Metabolic Versatility of Mycobacterium tuberculosis during Infection and Dormancy
DPS Chang, XL Guan - Metabolites, 2021 - mdpi.com
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is a highly
successful intracellular pathogen with the ability to withstand harsh conditions and reside …
successful intracellular pathogen with the ability to withstand harsh conditions and reside …
Exploiting cAMP signaling in Mycobacterium tuberculosis for drug discovery
D Kathayat, BC VanderVen - Trends in Microbiology, 2024 - cell.com
Mycobacterium tuberculosis (Mtb) replicates within host macrophages by adapting to the
stressful and nutritionally constrained environments in these cells. Exploiting these …
stressful and nutritionally constrained environments in these cells. Exploiting these …
[HTML][HTML] Metabolomic profiling reveals bacterial metabolic adaptation strategies and new metabolites
H Wang, LPS de Carvalho - Current Opinion in Chemical Biology, 2023 - Elsevier
How has metabolomics helped our understanding of infectious diseases? With the threat of
antimicrobial resistance to human health around the world, metabolomics has emerged as a …
antimicrobial resistance to human health around the world, metabolomics has emerged as a …
Mycobacterial regulatory systems involved in the regulation of gene expression under respiration-inhibitory conditions
Mycobacterium tuberculosis is the causative agent of tuberculosis. M. tuberculosis can
survive in a dormant state within the granuloma, avoiding the host-mounting immune attack …
survive in a dormant state within the granuloma, avoiding the host-mounting immune attack …
Metabolomics in clinical diagnosis, prognosis, and treatment of infectious diseases
Infectious diseases are one of the major causes of death worldwide. Therefore clinical
management of infectious disease requires robust biomarkers that have diagnostic and …
management of infectious disease requires robust biomarkers that have diagnostic and …
[PDF][PDF] Metabolic Versatility of Mycobacterium tuberculosis during Infection and Dormancy. Metabolites 2021, 11, 88
DPS Chang, XL Guan - 2021 - pdfs.semanticscholar.org
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is a highly
successful intracellular pathogen with the ability to withstand harsh conditions and reside …
successful intracellular pathogen with the ability to withstand harsh conditions and reside …
[LIBRO][B] The Phosphodiesterase, Rv0805, Is an Unheralded Component of TB Complex Mycobacterial Physiology in and Beyond Camp Homeostasis
JR McDowell - 2021 - search.proquest.com
Phosphodiesterases (PDEs) are integral components of 3', 5'-cyclic adenosine
monophosphate (cAMP) signaling pathways by degrading cAMP to modulate the …
monophosphate (cAMP) signaling pathways by degrading cAMP to modulate the …