Recent efforts to construct reference maps of cellular phenotypes have expanded the
volume and diversity of single-cell omics data, providing an unprecedented resource for …

The treatment options for advanced papillary thyroid cancer (PTC) and anaplastic thyroid
cancer (ATC) refractory to standard therapies are limited. Although anti-PD-1 therapy has a …

The applications of single-cell and spatial technologies in recent times have revolutionized
the present understanding of cellular states and the cellular heterogeneity inherent in …

Exponential accumulation of single-cell transcriptomes poses great challenge for efficient
assimilation. Here, we present an approach entitled generative pretraining from …

Accurate discrimination between patients with and without cancer from cfDNA is crucial for
early cancer diagnosis. Herein, we develop and validate a deep-learning-based model …

Single-cell RNA sequencing (scRNA-seq) is a key technology for investigating cell
development and analysing cell diversity across various diseases. However, the high …

The rapidly evolving realm of single-cell transcriptomics offers vital new perspectives into the
understanding of intra-and inter-cellular molecular dynamics governing development …