Pyrazoline hybrids as promising anticancer agents: An up-to-date overview
Pyrazolines are five-membered heterocycles possessing two adjacent nitrogens. They have
attracted significant attention from organic and medicinal chemists due to their potent …
attracted significant attention from organic and medicinal chemists due to their potent …
Discovery of anticancer agents from 2-pyrazoline-based compounds
QS Li, BN Shen, Z Zhang, S Luo… - Current medicinal …, 2021 - ingentaconnect.com
As nitrogen-containing five-membered heterocyclic structural units, the substituted pyrazole
derivatives have a broad spectrum of pharmacological activities, especially 4, 5-dihydro-1H …
derivatives have a broad spectrum of pharmacological activities, especially 4, 5-dihydro-1H …
Unveiling the Substituent Effects in the Stereochemistry of [3+ 2] Cycloaddition Reactions of Aryl‐and Alkyldiazomethylphosphonates with Norbornadiene within a …
Abstract The [3+ 2] cycloaddition (32CA) reactions of norbornadiene with aryl and alkyl
substituted diazomethylphosphonates (SDAPs) have been studied within the molecular …
substituted diazomethylphosphonates (SDAPs) have been studied within the molecular …
Diverse Pharmacological Potential of different Substituted Pyrazole Derivatives
The chemistry of heterocyclic compounds has been a topic of research interest. Some five-
membered heterocyclic compounds have been the subject of extensive research due to their …
membered heterocyclic compounds have been the subject of extensive research due to their …
[HTML][HTML] 2D/3D-QSAR Model Development Based on a Quinoline Pharmacophoric Core for the Inhibition of Plasmodium falciparum: An In Silico Approach with …
Malaria is an infectious disease caused by Plasmodium spp. parasites, with widespread
drug resistance to most antimalarial drugs. We report the development of two 3D-QSAR …
drug resistance to most antimalarial drugs. We report the development of two 3D-QSAR …
Synthesis, characterization and biological study of some new N-acetyl pyrazole derivatives
M Dhaduk, H Joshi - Current Chemistry Letters, 2022 - growingscience.com
A series of N-acetyl pyrazole derivatives, 1-acetyl-3-aryl-5-[5'-(4-nitrophenyl)-2'-furyl]-4, 5-
dihydro-1H-pyrazoles (5a-j) were synthesized by cyclocondensation reaction between 1-aryl …
dihydro-1H-pyrazoles (5a-j) were synthesized by cyclocondensation reaction between 1-aryl …
Facile Synthesis and Anticancer Evaluation of Novel 1-(Thiazol-2-yl)-3-(thiazol-5-yl)-5-(thiophen-2-yl) Pyrazolines
Some novel pyrazoline derivatives bearing thiazole and thiophene moieties have been
efficiently synthesized and characterized. The synthetic approach involves condensation of …
efficiently synthesized and characterized. The synthetic approach involves condensation of …
[HTML][HTML] In Silico Evaluation of Novel 2-Pyrazoline Carboxamide Derivatives as Potential Protease Inhibitors Against Plasmodium Parasites
Y Jimoh, IY Abdullah, AN Hamza, M Abdullahi… - Chemistry …, 2024 - mdpi.com
Malaria, a devastating disease caused by Plasmodium parasites, continues to pose a
significant threat to global health, with increasing resistance to current antimalarial drugs. In …
significant threat to global health, with increasing resistance to current antimalarial drugs. In …
[PDF][PDF] Synthesis of some new N-acyl derivatives of ferrocenyl pyrazolines and investigation of their cytotoxic effect
J Muškinja, J Luković, I Nikolić, D Baskić, Z Ratković - 2022 - sciforum.net
For several years, ferrocene moiety represents a significant part of the structure of different
biologically active compounds. Ferrocene is stable and non-toxic compound and as such …
biologically active compounds. Ferrocene is stable and non-toxic compound and as such …