Endocrine and paracrine regulation of birth at term and preterm

JRG Challis, SG Matthews, W Gibb, SJ Lye - Endocrine reviews, 2000 - academic.oup.com
We have examined factors concerned with the maintenance of uterine quiescence during
pregnancy and the onset of uterine activity at term in an animal model, the sheep, and in …

Pathogenesis of preterm labor and preterm premature rupture of membranes associated with intraamniotic infection

R Gomez, R Romero, SS Edwin… - Infectious Disease Clinics, 1997 - id.theclinics.com
A growing body of evidence supports a role for intrauterine infection in preterm labor and
preterm premature rupture of membranes (PROM). This article reviews the definition …

Periodontal therapy may reduce the risk of preterm low birth weight in women with peridotal disease: a randomized controlled trial

NJ López, PC Smith, J Gutierrez - Journal of periodontology, 2002 - Wiley Online Library
Background: Recent studies have suggested that periodontal disease is a risk factor for
preterm low birth weight (PLBW). A randomized controlled trial was undertaken to help …

The role of nuclear factor kappa B in human labour

TM Lindstrom, PR Bennett - Reproduction, 2005 - rep.bioscientifica.com
Preterm birth remains the leading cause of perinatal mortality and morbidity, largely as a
result of a poor understanding of the precise mechanisms controlling labour onset in …

Novel concepts on pregnancy clocks and alarms: redundancy and synergy in human parturition

R Menon, EA Bonney, J Condon… - Human reproduction …, 2016 - academic.oup.com
The signals and mechanisms that synchronize the timing of human parturition remain a
mystery and a better understanding of these processes is essential to avert adverse …

Pregnancy-associated liver diseases

NA Terrault, C Williamson - Gastroenterology, 2022 - Elsevier
The liver disorders unique to pregnancy include hyperemesis gravidarum, intrahepatic
cholestasis of pregnancy, acute fatty liver of pregnancy, and preeclampsia-associated …

[HTML][HTML] Fetal and maternal NLRP3 signaling is required for preterm labor and birth

K Motomura, R Romero, J Galaz, L Tao… - JCI insight, 2022 - ncbi.nlm.nih.gov
Preterm birth is the leading cause of neonatal morbidity and mortality worldwide. One of
every 4 preterm neonates is born to a mother with intra-amniotic inflammation driven by …

Molecular regulation of parturition: the role of the decidual clock

ER Norwitz, EA Bonney… - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
The timing of birth is a critical determinant of perinatal outcome. Despite intensive research,
the molecular mechanisms responsible for the onset of labor both at term and preterm …

The immunophenotype of amniotic fluid leukocytes in normal and complicated pregnancies

N Gomez‐Lopez, R Romero, Y Xu… - American Journal of …, 2018 - Wiley Online Library
Problem The immune cellular composition of amniotic fluid is poorly understood. Herein, we
determined: 1) the immunophenotype of amniotic fluid immune cells during the second and …

The role of prostaglandins in human parturition

W Gibb - Annals of medicine, 1998 - Taylor & Francis
Parturition is the process of giving birth, and the molecular mechanisms involved are still to
be elucidated. Among the various factors involved prostaglandins appear to have an …