Neuroinflammation play an important role in Alzheimer's disease pathogenesis. Advances in
molecular imaging using positron emission tomography have provided insights into the time …

Neuroinflammation plays a major role in the etiopathology of neurodegenerative diseases,
including Alzheimer and Parkinson diseases, frontotemporal lobar degeneration, and …

Inflammatory responses, manifested in excessive oxidative stress and microglia
overactivation, together with metal ion-triggered amyloid-beta (Aβ) deposition, are critical …

Alzheimer's disease (AD) is a devastating and irreversible neurodegenerative disorder with
unknown etiology. While its cause is unclear, a number of theories have been proposed to …

Abstract β-amyloid (Aβ) and tau aggregation as well as neuronal injury and atrophy (ATN)
are the major hallmarks of Alzheimer's disease (AD), and biomarkers for these hallmarks …

Plasma phosphorylated tau (p-tau) and glial fibrillary acidic protein (GFAP) both reflect early
changes in Alzheimer's disease (AD) pathology. Here, we compared the biomarker levels …

Neuroinflammation is a significant contributor to Alzheimer's disease (AD). Until now, PET
imaging of the translocator protein (TSPO) has been widely used to depict the neuroimmune …

Background Neuroinflammation, characterized by increased reactivity of microglia and
astrocytes in the brain, is known to be present at various stages of the Alzheimer's disease …

Background and Objectives Plasma β-amyloid42 (Aβ42)/Aβ40 levels have shown promise
in identifying Aβ-PET positive individuals. This study explored the concordance and …

Cognitive impairment (CI) is common in α-synucleinopathies, ie, Parkinson's disease, Lewy
bodies dementia, and multiple system atrophy. We summarize data from systematic …