Medicinal attributes of 1, 2, 3-triazoles: Current developments

D Dheer, V Singh, R Shankar - Bioorganic Chemistry, 2017 - Elsevier
Triazoles are important five-membered heterocyclic scaffold due to their extensive biological
activities. This framework can be readily obtained in good to excellent yields on the …

Recent progress on synthesis of functionalized 1, 5-disubstituted triazoles

MK Jaiswal, A Gupta, FJ Ansari… - Current Organic …, 2024 - benthamdirect.com
Immediately after the invention of 'Click Chemistry'in 2002, the regioselective 1, 2, 3-triazole
scaffolds resulted from respective organic azides and terminal alkynes under Cu (I) catalysis …

A Metal‐Free Three‐Component Reaction for the Regioselective Synthesis of 1, 4, 5‐Trisubstituted 1, 2, 3‐Triazoles

J Thomas, J John, N Parekh, W Dehaen - Angewandte Chemie, 2014 - Wiley Online Library
A metal‐free three‐component reaction to synthesize 1, 4, 5‐trisubstituted 1, 2, 3‐triazoles
from readily available building blocks, such as aldehydes, nitroalkanes, and organic azides …

Emerging approaches for the synthesis of triazoles: beyond metal-catalyzed and strain-promoted azide–alkyne cycloaddition

CGS Lima, A Ali, SS van Berkel… - Chemical …, 2015 - pubs.rsc.org
Metal-free 1, 3-dipolar cycloaddition reactions have proven to be a powerful tool for the
assembly of key heterocycles, in particular diversely functionalized 1, 2, 3-triazoles. A …

Synthesis of Multisubstituted 1, 2, 3-Triazoles: Regioselective Formation and Reaction Mechanism

TC Chi, PC Yang, SK Hung, HW Wu… - The Journal of …, 2024 - ACS Publications
A synthetically useful approach to functionalized triazoles is described via the reaction of β-
carbonyl phosphonates and azides. 1, 4-and 1, 5-disubstituted and 1, 4, 5-trisubstituted …

Metal-free syntheses of N-functionalized and NH-1, 2, 3-triazoles: an update on recent developments

T Opsomer, W Dehaen - Chemical Communications, 2021 - pubs.rsc.org
An overview of the latest developments in the metal-free synthesis of non-benzo-fused N-
functionalized and NH-1, 2, 3-triazoles is provided in this feature article. Synthetic studies …

Organocatalyzed Regioselective Synthesis of 1, 5‐Disubstituted 1, 2, 3‐Triazolyl Glycoconjugates

MK Jaiswal, A Gupta, MS Yadav… - … A European Journal, 2023 - Wiley Online Library
Abstract A novel organocatalyzed [3+ 2] cycloaddition reaction of nitroolefins with glycosyl
azides as well as organic azides has been developed for successful construction of 1, 5 …

An efficient one-pot strategy for the highly regioselective metal-free synthesis of 1, 4-disubstituted-1, 2, 3-triazoles

A Ali, AG Corrêa, D Alves… - Chemical …, 2014 - pubs.rsc.org
A simple and efficient metal-free methodology for the regioselective synthesis of 1, 4-
disubstituted-1, 2, 3-triazoles has been developed by applying a novel inverse electron …

An Overview on the Chemical N‐Functionalization of Sugars and Formation of N‐Glycosides

R Sangwan, A Khanam… - European Journal of …, 2020 - Wiley Online Library
Its even more than a centennial that the systematic researches of chemical alteration of
sugars have been advancing. Out of all the interest in the field of N‐glycoside has …

Organocatalytic 1, 3-dipolar cycloaddition reaction of α, β-unsaturated ketones with azides through iminium catalysis

W Li, Z Du, K Zhang, J Wang - Green Chemistry, 2015 - pubs.rsc.org
Organocatalytic 1,3-dipolar cycloaddition reaction of α,β-unsaturated ketones with azides
through iminium catalysis - Green Chemistry (RSC Publishing) DOI:10.1039/C4GC01929F …