Therapeutic potential of coumarins as antiviral agents

MZ Hassan, H Osman, MA Ali, MJ Ahsan - European journal of medicinal …, 2016 - Elsevier
Coumarins have received a considerable attention in the last three decades as a lead
structures for the discovery of orally bioavailable non-peptidic antiviral agents. A lot of …

The antioxidant activity of coumarins and flavonoids

G Borges Bubols, D da Rocha Vianna… - Mini reviews in …, 2013 - ingentaconnect.com
Coumarins and flavonoids are heterocyclic molecules that have been associated with
beneficial effects on human health, such as reducing the risk of cancer, diabetes …

Coumarin-based derivatives with potential anti-HIV activity

Z Xu, Q Chen, Y Zhang, C Liang - Fitoterapia, 2021 - Elsevier
Acquired immunodeficiency syndrome (AIDS), as a result of human immunodeficiency virus
(HIV) infection which leads to severe suppression of immune functions, is an enormous …

Recent advances in the synthesis of coumarin derivatives via Knoevenagel condensation: A review

RH Vekariya, HD Patel - Synthetic Communications, 2014 - Taylor & Francis
The synthesis of coumarins through Knoevenagel condensation is one of the most important
processes in synthetic organic chemistry and medicinal chemistry. Compounds including a …

Medicinal plants used in the treatment of human immunodeficiency virus

B Salehi, NVA Kumar, B Şener, M Sharifi-Rad… - International journal of …, 2018 - mdpi.com
Since the beginning of the epidemic, human immunodeficiency virus (HIV) has infected
around 70 million people worldwide, most of whom reside is sub-Saharan Africa. There …

Plant coumarins with anti-HIV activity: Isolation and mechanisms of action

AD Sharapov, RF Fatykhov, IA Khalymbadzha… - International Journal of …, 2023 - mdpi.com
This review summarizes and systematizes the literature on the anti-HIV activity of plant
coumarins with emphasis on isolation and the mechanism of their antiviral action. This …

The structure and pharmacological functions of coumarins and their derivatives

L Wu, X Wang, W Xu, F Farzaneh… - Current medicinal …, 2009 - ingentaconnect.com
Coumarins are of many different structures. They constitute an important class of
pharmacological agents possessing a range of different physiological activities including …

Pharmacological and nutritional effects of natural coumarins and their structure–activity relationships

JJ Zhu, JG Jiang - Molecular nutrition & food research, 2018 - Wiley Online Library
Coumarins are fused benzene and pyrone ring systems with a wide spectrum of
bioactivities, including antitumor, anti‐inflammation, antiviral, and antibacterial effects. In this …

Synthesis and evaluation of the antioxidant and anti-inflammatory activity of novel coumarin-3-aminoamides and their alpha-lipoic acid adducts

G Melagraki, A Afantitis, O Igglessi-Markopoulou… - European journal of …, 2009 - Elsevier
In the present work a series of novel coumarin-3-carboxamides and their hybrids with the
alpha-lipoic acid were designed, synthesized and tested as potent antioxidant and anti …

Free radical scavenging activity and reducing power of Acacia nilotica wood lignin

KR Aadil, A Barapatre, S Sahu, H Jha… - International journal of …, 2014 - Elsevier
Nine different fractions of lignin extracted by alkali, hot water and organosolv methods from
Acacia wood powder were assessed for antioxidants activity. Results indicated that …