Electrospun polymer micro/nanofibers have been widely explored as platforms for controlled
delivery of therapeutic agents. Electrospun fibers are featured by large surface area, high …

Exploring innovative solutions to improve the healthcare of the aging and diseased
population continues to be a global challenge. Among a number of strategies toward this …

Abstract Poly (lactic acid)(PLA) is a synthetic polyester that has shown extensive utility in
tissue engineering. Synthesized either by ring opening polymerization or polycondensation …

Collagen is the most abundant structural protein of connective tissues including skin,
tendon, bone and cartilage in mammals. The complicated biosynthesis of nature collagen in …

Poly (lactic acid)(PLA) is an aliphatic polyester that can be derived from natural and
renewable resources. Owing to favorable features, such as biocompatibility …

Tissue engineered nerve grafts (TENGs) have emerged as a potential alternative to
autologous nerve grafts, the gold standard for peripheral nerve repair. Typically, TENGs are …

The choice of biomaterials available for regenerative medicine continues to grow rapidly,
with new materials often claiming advantages over the short-comings of those already in …

The treatment of long-gap (> 10 mm) peripheral nerve injury (PNI) and spinal cord injury
(SCI) remains a continuous challenge due to limited native tissue regeneration capabilities …

Peripheral nerve injury (PNI), one of the most common concerns following trauma, can result
in a significant loss of sensory or motor function. Restoration of the injured nerves requires a …

Repairing peripheral nerve injury, especially long-range defects of thick nerves, is a great
challenge in the clinic due to their limited regeneration capability. Most FDA-approved nerve …