Flaviviruses, such as dengue, Japanese encephalitis, tick-borne encephalitis, West Nile,
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …

Gene drives may be capable of addressing ecological problems by altering entire
populations of wild organisms, but their use has remained largely theoretical due to …

Human pathogens that are transmitted by insects are a global problem, particularly those
vectored by mosquitoes; for example, malaria parasites transmitted by Anopheles species …

Arthropod-borne viruses (arboviruses) circulate in nature between arthropod vectors and
vertebrate hosts. Arboviruses often cause devastating diseases in vertebrate hosts, but they …

Recently, the Vaccines to Vaccinate (v2V) initiative was reconfigured into the Partnership for
Dengue Control (PDC), a multi-sponsored and independent initiative. This redirection is …

Aedes aegypti is the principal mosquito vector for many arboviruses that increasingly infect
millions of people every year. With an escalating burden of infections and the relative failure …

RNA interference (RNAi), the sequence-specific suppression of gene expression, offers
great opportunities for insect science, especially to analyze gene function, manage pest …

Genetic strategies that reduce or block pathogen transmission by mosquitoes have been
proposed as a means of augmenting current control measures to reduce the growing burden …

SUMMARY West Nile Virus was introduced into the Western Hemisphere during the late
summer of 1999 and has been causing significant and sometimes severe human diseases …

Genetics can potentially provide new, species-specific, environmentally friendly methods for
mosquito control. Genetic control strategies aim either to suppress target populations or to …