Engineering a highly regioselective fungal peroxygenase for the synthesis of hydroxy fatty acids
P Gomez de Santos, A González‐Benjumea… - Angewandte …, 2023 - Wiley Online Library
The hydroxylation of fatty acids is an appealing reaction in synthetic chemistry, although the
lack of selective catalysts hampers its industrial implementation. In this study, we have …
lack of selective catalysts hampers its industrial implementation. In this study, we have …
From alkanes to carboxylic acids: Terminal oxygenation by a fungal peroxygenase
A Olmedo, C Aranda, JC Del Río, J Kiebist… - Angewandte …, 2016 - Wiley Online Library
A new heme–thiolate peroxidase catalyzes the hydroxylation of n‐alkanes at the terminal
position—a challenging reaction in organic chemistry—with H2O2 as the only cosubstrate …
position—a challenging reaction in organic chemistry—with H2O2 as the only cosubstrate …
Comparing the Catalytic and Structural Characteristics of a 'Short' Unspecific Peroxygenase (UPO) Expressed in Pichia pastoris and Escherichia coli
WXQ Robinson, T Mielke, B Melling, A Cuetos… - …, 2023 - Wiley Online Library
Unspecific peroxygenases (UPOs) have emerged as valuable tools for the oxygenation of
non‐activated carbon atoms, as they exhibit high turnovers, good stability and depend only …
non‐activated carbon atoms, as they exhibit high turnovers, good stability and depend only …
Selective Oxidation of Vitamin D3 Enhanced by Long‐Range Effects of a Substrate Channel Mutation in Cytochrome P450BM3 (CYP102A1)
W Chen, JNC Lynch, C Bustamante… - … A European Journal, 2024 - Wiley Online Library
Vitamin D deficiency affects nearly half the population, with many requiring or opting for
supplements with vitamin D3 (VD3), the precursor of vitamin D (1α, 25‐dihydroxyVD3). 25 …
supplements with vitamin D3 (VD3), the precursor of vitamin D (1α, 25‐dihydroxyVD3). 25 …