Possible role of Porphyromonas gingivalis in orodigestive cancers

I Olsen, Ö Yilmaz - Journal of oral microbiology, 2019 - Taylor & Francis
There is increasing evidence for an association between periodontitis/tooth loss and oral,
gastrointestinal, and pancreatic cancers. Periodontal disease, which is characterized by …

Immunological Pathways Triggered by Porphyromonas gingivalis and Fusobacterium nucleatum: Therapeutic Possibilities?

KQ De Andrade, CLC Almeida-da-Silva… - Mediators of …, 2019 - Wiley Online Library
Porphyromonas gingivalis (P. gingivalis) and Fusobacterium nucleatum (F. nucleatum) are
Gram‐negative anaerobic bacteria possessing several virulence factors that make them …

Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles

AJ Fleetwood, MKS Lee, W Singleton… - Frontiers in cellular …, 2017 - frontiersin.org
Porphyromonas gingivalis is one of the bacterial species most closely associated with
periodontitis and can shed large numbers of outer membrane vesicles (OMVs), which are …

Regulatory effects of oral microbe on intestinal microbiota and the illness

Y Lu, Z Li, X Peng - Frontiers in Cellular and Infection Microbiology, 2023 - frontiersin.org
Over the past decade, the association between oral health, intestinal microbiota, and
systemic diseases has been further validated. Some oral microbial species have been …

Oral-intestinal microbiota in colorectal cancer: inflammation and immunosuppression

S Mo, H Ru, M Huang, L Cheng, X Mo… - Journal of Inflammation …, 2022 - Taylor & Francis
It is widely recognized that microbial disorders are involved in the pathogenesis of many
malignant tumors. The oral and intestinal tract are two of the overriding microbial habitats in …

Porphyromonas gingivalis traffics into endoplasmic reticulum-rich-autophagosomes for successful survival in human gingival epithelial cells

K Lee, JAS Roberts, CH Choi, KR Atanasova, Ö Yilmaz - Virulence, 2018 - Taylor & Francis
Porphyromonas gingivalis, an opportunistic pathogen usurps gingival epithelial cells (GECs)
as primary intracellular niche for its colonization in the oral mucosa. However, the precise …

Melatonin elevated Sclerotinia sclerotiorum resistance via modulation of ATP and glucosinolate biosynthesis in Brassica rapa ssp. pekinensis

Z Teng, Y Yu, Z Zhu, SB Hong, B Yang, Y Zang - Journal of proteomics, 2021 - Elsevier
Sclerotinia stem rot is a common disease found in Brassica rapa that is caused by the
necrotic plant pathogen Sclerotinia sclerotiorum. Melatonin (MT) has known biological …

Illuminating the oral microbiome: cellular microbiology

RJ Lamont, DP Miller, J Bagaitkar - FEMS Microbiology …, 2023 - academic.oup.com
Epithelial cells line mucosal surfaces such as in the gingival crevice and provide a barrier to
the ingress of colonizing microorganisms. However, epithelial cells are more than a passive …

Macrophages immunomodulation induced by Porphyromonas gingivalis and oral antimicrobial peptides

BE Blancas-Luciano, J Zamora-Chimal… - Odontology, 2023 - Springer
Porphyromonas gingivalis is a keystone pathogen associated with periodontitis
development, a chronic inflammatory pathology characterized by the destruction of the …

A novel kinase function of a nucleoside‐diphosphate‐kinase homologue in Porphyromonas gingivalis is critical in subversion of host cell apoptosis by targeting heat …

J Lee, JAS Roberts, KR Atanasova… - Cellular …, 2018 - Wiley Online Library
We have previously shown that a homologue of a conserved nucleoside‐diphosphate‐
kinase (Ndk) family of multifunctional enzymes and secreted molecule in Porphyromonas …