Therapeutic implications of cyclooxygenase (COX) inhibitors in ischemic injury
Introduction Ischemia–reperfusion injury (IRI) is the inexplicable aggravation of cellular
dysfunction that results in blood flow restoration to previously ischemic tissues. COX …
dysfunction that results in blood flow restoration to previously ischemic tissues. COX …
Dysbiosis and Alzheimer's disease: a role for chronic stress?
Alzheimer's disease (AD) is an incurable, neuropsychiatric, pathological condition that
deteriorates the worth of geriatric lives. AD is characterized by aggregated senile amyloid …
deteriorates the worth of geriatric lives. AD is characterized by aggregated senile amyloid …
[HTML][HTML] Animal models of diabetic microvascular complications: Relevance to clinical features
Diabetes has become more common in recent years worldwide, and this growth is projected
to continue in the future. The primary concern with diabetes is develo** various …
to continue in the future. The primary concern with diabetes is develo** various …
Advancements and challenges of fuel cell integration in electric vehicles: A comprehensive analysis
Fuel cell technology emerges as a promising green solution, offering mitigation to global
warming, air pollution, and energy crises. This eco-friendly approach is witnessing a surge …
warming, air pollution, and energy crises. This eco-friendly approach is witnessing a surge …
Peroxisome proliferator-activated receptor-gamma (PPAR-ɣ): molecular effects and its importance as a novel therapeutic target for cerebral ischemic injury
Cerebral ischemic injury is a leading cause of death and long-term disability throughout the
world. Peroxisome proliferator-activated receptor gamma (PPAR-ɣ) is a ligand-activated …
world. Peroxisome proliferator-activated receptor gamma (PPAR-ɣ) is a ligand-activated …
Emerging targets for modulation of immune response and inflammation in stroke
The inflammatory and immunological responses play a significant role after stroke. The
innate immune activation stimulated by microglia during stroke results in the migration of …
innate immune activation stimulated by microglia during stroke results in the migration of …
Identification of drug-drug interactions using chemical interactions
Background: One drug can affect the activity of another when they are administered
together, which can cause adverse drug reactions or sometimes improve therapeutic effects …
together, which can cause adverse drug reactions or sometimes improve therapeutic effects …
Pharmacological modulation of cytokines correlating neuroinflammatory cascades in epileptogenesis
S Vishwakarma, S Singh, TG Singh - Molecular Biology Reports, 2022 - Springer
Epileptic seizure-induced brain injuries include activation of neuroimmune response with
activation of microglia, astrocytes cells releasing neurotoxic inflammatory mediators …
activation of microglia, astrocytes cells releasing neurotoxic inflammatory mediators …
Neuro-inflammation, blood-brain barrier, seizures and autism
Abstract Many children with Autism Spectrum Diseases (ASD) present with seizure activity,
but the pathogenesis is not understood. Recent evidence indicates that neuro-inflammation …
but the pathogenesis is not understood. Recent evidence indicates that neuro-inflammation …
Evidence for the involvement of the dopaminergic system in seizure and oxidative damage induced by tramadol
Tramadol (TR) is a synthetic analgesic drug with central function that can induce seizures
even at therapeutic doses. The exact mechanism of TR effect on seizure generation is not …
even at therapeutic doses. The exact mechanism of TR effect on seizure generation is not …