A review of circulating tumour cell enrichment technologies

AJ Rushton, G Nteliopoulos, JA Shaw, RC Coombes - Cancers, 2021‏ - mdpi.com
Simple Summary Circulating tumour cells (CTCs) are cancer cells shed into the bloodstream
from tumours and their analysis can provide important insights into cancer detection and …

Current detection technologies for circulating tumor cells

Z Shen, A Wu, X Chen - Chemical Society Reviews, 2017‏ - pubs.rsc.org
Circulating tumor cells (CTCs) are cancer cells that circulate in the blood stream after being
naturally shed from original or metastatic tumors, and can lead to a new fatal metastasis …

Technologies for circulating tumor cell separation from whole blood

P Bankó, SY Lee, V Nagygyörgy, M Zrínyi… - Journal of hematology & …, 2019‏ - Springer
The importance of early cancer diagnosis and improved cancer therapy has been clear for
years and has initiated worldwide research towards new possibilities in the care strategy of …

[HTML][HTML] Microfluidic-based technologies for CTC isolation: a review of 10 years of intense efforts towards liquid biopsy

L Descamps, D Le Roy, AL Deman - International Journal of Molecular …, 2022‏ - mdpi.com
The selection of circulating tumor cells (CTCs) directly from blood as a real-time liquid
biopsy has received increasing attention over the past ten years, and further analysis of …

Third generation EGFR TKIs: current data and future directions

CS Tan, NB Kumarakulasinghe, YQ Huang, YLE Ang… - Molecular cancer, 2018‏ - Springer
Acquired T790 M mutation is the commonest cause of resistance for advanced non-small
cell lung cancer (NSCLC) epidermal growth factor receptor (EGFR) mutant patients who had …

Advancing the speed, sensitivity and accuracy of biomolecular detection using multi-length-scale engineering

SO Kelley, CA Mirkin, DR Walt, RF Ismagilov… - Nature …, 2014‏ - nature.com
Rapid progress in identifying disease biomarkers has increased the importance of creating
high-performance detection technologies. Over the last decade, the design of many …

Size-based separation methods of circulating tumor cells

SJ Hao, Y Wan, YQ **a, X Zou, SY Zheng - Advanced drug delivery reviews, 2018‏ - Elsevier
Circulating tumor cells (CTCs) originate from the primary tumor mass and enter into the
peripheral bloodstream. Compared to other “liquid biopsy” portfolios such as exosome …

A new device for rapid isolation by size and characterization of rare circulating tumor cells

I Desitter, BS Guerrouahen, N Benali-Furet… - Anticancer …, 2011‏ - ar.iiarjournals.org
Background: Circulating tumor cells (CTCs) likely derive from clones in the primary tumor,
suggesting that they can be used for all biological tests applying to the primary cells …

3D microfilter device for viable circulating tumor cell (CTC) enrichment from blood

S Zheng, HK Lin, B Lu, A Williams, R Datar… - Biomedical …, 2011‏ - Springer
Detection of circulating tumor cells has emerged as a promising minimally invasive
diagnostic and prognostic tool for patients with metastatic cancers. We report a novel three …

Cell softness regulates tumorigenicity and stemness of cancer cells

J Lv, Y Liu, F Cheng, J Li, Y Zhou, T Zhang… - The EMBO …, 2021‏ - embopress.org
Identifying and sorting highly tumorigenic and metastatic tumor cells from a heterogeneous
cell population is a daunting challenge. Here, we show that microfluidic devices can be used …