Cortical gain regulation allows neurons to respond adaptively to changing inputs. Neural
gain is modulated by internal and external influences, including attentional and arousal …

Sensorineural hearing loss induced by noise or ototoxic drug exposure reduces the neural
activity transmitted from the cochlea to the central auditory system. Despite a reduced …

Sensory organ damage induces a host of cellular and physiological changes in the
periphery and the brain. Here, we show that some aspects of auditory processing recover …

Adaptation is an essential feature of auditory neurons, which reduces their responses to
unchanging and recurring sounds and allows their response properties to be matched to the …

The purpose of the current review is to propose a model highlighting the putative
connections between hearing loss and the phantom perception of tinnitus (tinnitus being …

The neuroscience of tinnitus represents an ideal model to explore central issues in brain
functioning such as the formation of auditory percepts, in addition to opening up new …

The auditory system must represent sounds with a wide range of statistical properties. One
important property is the spectrotemporal contrast in the acoustic environment: the variation …

We examined the activity of individual cells in the primate anterior cingulate cortex during an
economic choice task. In the experiments, monkeys chose between different juices offered in …

Adaptation is a common principle that recurs throughout the nervous system at all stages of
processing. This principle manifests in a variety of phenomena, from spike frequency …

Subjective tinnitus is generally assumed to be a consequence of hearing loss. In animal
studies it has been demonstrated that acoustic trauma induced cochlear damage can lead to …