Before a lead compound goes through a clinical trial, preclinical studies utilize two‐
dimensional (2D) in vitro models and animal models to study the pharmacodynamics and …

Abstract Copper oxide nanoparticles (CuO NPs) have received increasing interest due to
their distinctive properties, including small particle size, high surface area, and reactivity …

The high frequency of using engineered nanoparticles in various medical applications
entails a deep understanding of their interaction with biological macromolecules. Molecular …

Background Epidemiological and animal studies provide compelling indications that
environmental and engineered nanomaterials (NMs) pose a risk for pregnancy, fetal …

The growing nanoparticulate pollution (eg engineered nanoparticles (NPs) or nanoplastics)
has been shown to pose potential threats to human health. In particular, sensitive …

Abstract Background Titanium dioxide (TiO 2) is broadly used in common consumer goods,
including as a food additive (E171 in Europe) for colouring and opacifying properties. The …

BACKGROUND Nanotechnology involves the engineering of structures on a molecular
level. Nanomedicine and nano-delivery systems have been designed to deliver therapeutic …

Early human life is considered a critical window of susceptibility to external exposures.
Infants are exposed to a multitude of environmental factors, collectively referred to as the …

Background Nanoparticles, which are exposed to biological fluids are rapidly interacting
with proteins and other biomolecules forming a corona. In addition to dimension, charge and …

Nanomedicine has emerged as a promising therapeutic approach, but its translation to the
clinic has been hindered by the lack of cellular models to anticipate how tumor cells will …