A sparse PLS for variable selection when integrating omics data

KA Lê Cao, D Rossouw, C Robert-Granié… - … applications in genetics …, 2008 - degruyter.com
Recent biotechnology advances allow for multiple types of omics data, such as
transcriptomic, proteomic or metabolomic data sets to be integrated. The problem of feature …

Generating Realistic In Silico Gene Networks for Performance Assessment of Reverse Engineering Methods

D Marbach, T Schaffter, C Mattiussi… - Journal of computational …, 2009 - liebertpub.com
Reverse engineering methods are typically first tested on simulated data from in silico
networks, for systematic and efficient performance assessment, before an application to real …

A statistical model for describing and simulating microbial community profiles

S Ma, B Ren, H Mallick, YS Moon… - PLoS computational …, 2021 - journals.plos.org
Many methods have been developed for statistical analysis of microbial community profiles,
but due to the complex nature of typical microbiome measurements (eg sparsity, zero …

A new measure for gene expression biclustering based on non-parametric correlation

JL Flores, I Inza, P Larranaga, B Calvo - Computer methods and programs …, 2013 - Elsevier
Background One of the emerging techniques for performing the analysis of the DNA
microarray data known as biclustering is the search of subsets of genes and conditions …

Using generalized procrustes analysis (GPA) for normalization of cDNA microarray data

H **ong, D Zhang, CJ Martyniuk, VL Trudeau, X **a - Bmc Bioinformatics, 2008 - Springer
Background Normalization is essential in dual-labelled microarray data analysis to remove
non-biological variations and systematic biases. Many normalization methods have been …

Segmentation of microarray images using pixel classification—Comparison with clustering-based methods

N Giannakeas, PS Karvelis, TP Exarchos… - Computers in biology …, 2013 - Elsevier
OBJECTIVE: DNA microarray technology yields expression profiles for thousands of genes,
in a single hybridization experiment. The quantification of the expression level is performed …

Microarray data normalization and robust detection of rhythmic features

Y Larriba, C Rueda, MA Fernández… - Microarray …, 2019 - Springer
Data derived from microarray technologies are generally subject to various sources of noise
and accordingly the raw data are pre-processed before formally analysed. Data …

[HTML][HTML] A flexible microarray data simulation model

D Dembélé - Microarrays, 2013 - mdpi.com
Microarray technology allows monitoring of gene expression profiling at the genome level.
This is useful in order to search for genes involved in a disease. The performances of the …

Evaluating the performance of microarray segmentation algorithms

A Lehmussola, P Ruusuvuori, O Yli-Harja - Bioinformatics, 2006 - academic.oup.com
Motivation: Although numerous algorithms have been developed for microarray
segmentation, extensive comparisons between the algorithms have acquired far less …

Machine learning and genetic regulatory networks: a review and a roadmap

C Fogelberg, V Palade - Foundations of Computational, Intelligence …, 2009 - Springer
Genetic regulatory networks (GRNs) are causal structures which can be represented as
large directed graphs. Their inference is a central problem in bioinformatics. Because of the …