It was shown early in this century that certain porphyrins are photosensitizers of the
photodynamic type, ie, they sensitize the photooxidative damage of biological systems on …

Most types of molecules of biological importance are relatively insensitive to direct eflFects
of" light"* since they do not absorb radia tion in this v^ avelength range. However, a large …

If trypsin is illuminated with visible light in the presence of an appropriate sensitizing dye and
oxygen, a loss of enzymatic activity is observed. This phenomenon is called photodynamic …

The irradiation of horse and sperm‐whale Fe 3* or Fe 2* myoglobins with visible light
showed that axial ligands that render the heme diamagnetic (eg O2, CO or CN‐) endow the …

Typical chemical reactions of singlet molecular oxygen with organic substances as well as
its disruptive influence on biological systems (the photodynamic effect) are described. The …

Almost all kinds of biological macromolecules, including polysaccharides, nucleic acids and
proteins, are oxidized upon illumination in the presence of sensitizing dyes and molecular …

In 1900, Raab'reported that living cells could be killed by illumination in the presence of
certain dyes; a short time later it was found that molecular oxygen was required for this …

The normal photobiological processes characteristic of living material must be sensitized by
appropriate pigments since molecules such as carbo hydrates, proteins, fats, nucleic acids …