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Visible-to-NIR-light activated release: from small molecules to nanomaterials
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
Local translation in neurons: visualization and function
Neurons are among the most compartmentalized and interactive of all cell types. Like all
cells, neurons use proteins as the main sensors and effectors. The modification of the …
cells, neurons use proteins as the main sensors and effectors. The modification of the …
Mechanisms of drug release in nanotherapeutic delivery systems
PT Wong, SK Choi - Chemical reviews, 2015 - ACS Publications
Targeted drug delivery refers to an established therapeutic strategy that develops platforms
and nanoscale devices for selective delivery of small drug molecules and therapeutic genes …
and nanoscale devices for selective delivery of small drug molecules and therapeutic genes …
mRNA transport & local translation in neurons
Highlights•∼ 2550 mRNA species are localized in dendrites and/or axons.•The alternative
usage of 3′ UTR isoforms dictates the fate of an mRNA molecule.•Novel multiplexed FISH …
usage of 3′ UTR isoforms dictates the fate of an mRNA molecule.•Novel multiplexed FISH …
Biologically active molecules with a “light switch”
Biologically active compounds which are light‐responsive offer experimental possibilities
which are otherwise very difficult to achieve. Since light can be manipulated very precisely …
which are otherwise very difficult to achieve. Since light can be manipulated very precisely …
Light-triggered release of photocaged therapeutics-Where are we now?
The current available therapeutics face several challenges such as the development of ideal
drug delivery systems towards the goal of personalized treatments for patients benefit. The …
drug delivery systems towards the goal of personalized treatments for patients benefit. The …
From one‐photon to two‐photon probes:“Caged” compounds, actuators, and photoswitches
G Bort, T Gallavardin, D Ogden… - Angewandte Chemie …, 2013 - Wiley Online Library
Molecular systems that can be remotely controlled by light are gaining increasing
importance in cell biology, physiology, and neurosciences because of the spatial and …
importance in cell biology, physiology, and neurosciences because of the spatial and …
Dendrimer advances for the central nervous system delivery of therapeutics
L Xu, H Zhang, Y Wu - ACS chemical neuroscience, 2014 - ACS Publications
The effectiveness of noninvasive treatment for central nervous system (CNS) diseases is
generally limited by the poor access of therapeutic agents into the CNS. Most CNS drugs …
generally limited by the poor access of therapeutic agents into the CNS. Most CNS drugs …
Photochemical control of biological processes
Photochemical regulation of biological processes offers a high level of control to study
intracellular mechanisms with unprecedented spatial and temporal resolution. This report …
intracellular mechanisms with unprecedented spatial and temporal resolution. This report …
Principles and applications of the photochemical control of cellular processes
A Deiters - Chembiochem: a European journal of chemical …, 2010 - pmc.ncbi.nlm.nih.gov
Biological processes, particularly gene function, are naturally regulated with high
spatiotemporal resolution in single cells and multicellular organisms. The activity of genes …
spatiotemporal resolution in single cells and multicellular organisms. The activity of genes …