Post mortem redistribution of drugs: current state of knowledge

C Sastre, C Bartoli, V Baillif-Couniou… - Current …, 2017 - ingentaconnect.com
Background: Drug concentrations obtained from post mortem samples do not necessarily
reflect the concentrations at the time of death, and variations of concentration may be …

The current state and future directions of skeletal toxicology: Forensic and humanitarian implications of a proposed model for the in vivo incorporation of drugs into the …

KM Rubin - Forensic Science International, 2018 - Elsevier
At present, the inability to meaningfully and reliably conduct toxicological testing on human
skeletal material represents a significant gap in forensic practice, especially in a time when …

Pitfalls of toxicological investigations in hair, bones, and nails in extensively decomposed bodies: illustration with two cases

JF Wiart, F Hakim, A Andry, C Eiden, G Drevin… - International Journal of …, 2020 - Springer
It is difficult to carry out toxicological investigations in biological samples collected from
extensively decomposed bodies and to interpret obtained results as several pitfalls should …

How do drugs affect the skeleton? Implications for forensic anthropology

N Márquez-Grant, E Baldini, V Jeynes… - Biology, 2022 - mdpi.com
Simple Summary Forensic anthropologists analyze human remains to assist in the
identification of the deceased, predominantly by assessing age-at-death, sex, stature …

Detecting drugs in dry bone: A pilot study of skeletal remains with a post-mortem interval over 23 years

G Giordano, L Biehler-Gomez, P Seneci… - International Journal of …, 2021 - Springer
In decomposed or skeletonized bodies, conventional matrices used in forensic toxicology
may no longer be available for analysis. The aim of this paper was to test the survival and …

Drugs in bone: Detectability of substances of toxicological interest in different states of preservation

L Franceschetti, D Di Candia… - Journal of Forensic …, 2021 - Wiley Online Library
In forensic contexts of advanced decomposition, when conventional matrices are no longer
available for toxicological analyses, finding alternative matrices is necessary. The skeleton …

Development and validation of a gas chromatography–mass spectrometry method for opiates and cocaine in human bone

L Fernandez-Lopez, A Luna-Maldonado… - … of Pharmaceutical and …, 2019 - Elsevier
A method based on gas chromatography–mass spectrometry (GC–MS) is described for the
determination of opioids (6-monoacetylmorphine, morphine, methadone and tramadol) and …

Distribution of methadone and metabolites in skeletal tissue

M Vandenbosch, T Somers… - Journal of Analytical …, 2018 - academic.oup.com
In forensic toxicology, when extended time has elapsed before discovery of the body, the
most commonly analyzed specimens are often degraded or not available at all due to …

In the case of extensively putrefied bodies, the analysis of entomological samples may support and complement the toxicological results obtained with other …

SM Aly, A Gish, F Hakim, D Guelmi, V Mesli, V Hédouin… - Legal Medicine, 2023 - Elsevier
Entomotoxicological analysis is not part of routine toxicological analysis. This work aims to
present two cases to illustrate the potential of entomological samples as complementary …

Development and Validation of a Method for the Analysis of Bisoprolol and Atenolol in Human Bone

L Fernandez-Lopez, M Pellegrini, MC Rotolo, A Luna… - Molecules, 2019 - mdpi.com
A method based on gas chromatography–mass spectrometry (GC–MS) is described for the
determination of bisoprolol and atenolol in human bone. After the addition of lobivolol as …