Metal-based photosensitizers as inducers of regulated cell death mechanisms

Y Zhang, BT Doan, G Gasser - Chemical reviews, 2023 - ACS Publications
Over the last few decades, various forms of regulated cell death (RCD) have been
discovered and were found to improve cancer treatment. Although there are several reviews …

Near-infrared metal agents assisting precision medicine: from strategic design to bioimaging and therapeutic applications

C Li, Y Pang, Y Xu, M Lu, L Tu, Q Li… - Chemical Society …, 2023 - pubs.rsc.org
Metal agents have made incredible strides in preclinical research and clinical applications in
recent years, but their short emission/absorption wavelengths continue to be a barrier to …

Minimally invasive nanomedicine: nanotechnology in photo-/ultrasound-/radiation-/magnetism-mediated therapy and imaging

J Ouyang, A **e, J Zhou, R Liu, L Wang, H Liu… - Chemical Society …, 2022 - pubs.rsc.org
Traditional treatments such as chemotherapy and surgery usually cause severe side effects
and excruciating pain. The emergence of nanomedicines and minimally invasive therapies …

Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Immunogenic cell death inducing metal complexes for cancer therapy

L Zhang, N Montesdeoca, J Karges… - Angewandte Chemie …, 2023 - Wiley Online Library
Cancer is one of the deadliest diseases worldwide. Recent statistics have shown that
metastases and tumor relapse are the leading causes of cancer‐associated deaths. While …

Combination of light and Ru (II) polypyridyl complexes: Recent advances in the development of new anticancer drugs

L Conti, E Macedi, C Giorgi, B Valtancoli… - Coordination Chemistry …, 2022 - Elsevier
The increasing impact of cancer on worldwide mortality makes the research of novel
chemotherapeutic agents a current and challenging issue. In the recent years, transition …

Photodynamic-based combinatorial cancer therapy strategies: Tuning the properties of nanoplatform according to oncotherapy needs

C Chen, C Wu, J Yu, X Zhu, Y Wu, J Liu… - Coordination Chemistry …, 2022 - Elsevier
In recent years, the wide application of photodynamic therapy (PDT) in the field of
biomedicine has proved its significance in cancer treatment. A variety of nanomaterials are …

Structurally simple osmium (II) polypyridyl complexes as photosensitizers for photodynamic therapy in the near infrared

A Mani, T Feng, A Gandioso, R Vinck… - Angewandte …, 2023 - Wiley Online Library
Five osmium (II) polypyridyl complexes of the general formula [Os (4, 7‐diphenyl‐1, 10‐
phenanthroline) 2L] 2+ were synthesized as photosensitizers for photodynamic therapy by …

An osmium-peroxo complex for photoactive therapy of hypoxic tumors

N Lu, Z Deng, J Gao, C Liang, H **a… - Nature Communications, 2022 - nature.com
The limited therapeutic effect on hypoxic and refractory solid tumors has hindered the
practical application of photodynamic therapy. Herein, we report our investigation of an …

Ru (II) containing photosensitizers for photodynamic therapy: A critique on reporting and an attempt to compare efficacy

MA Munegowda, A Manalac, M Weersink… - Coordination chemistry …, 2022 - Elsevier
Ruthenium (II)-based coordination complexes have emerged as photosensitizers (PSs) for
photodynamic therapy (PDT) in oncology as well as antimicrobial indications and have great …