Computational modelling of the lungs is an active field of study that integrates computational
advances with lung biophysics, biomechanics, physiology and medical imaging to promote …

Respiratory oscillometry (also known as the forced oscillation technique) is increasingly
contributing to lung function studies in clinical routine and research, as a result of its …

Background Persistent bronchodilator response (BDR) following diagnosis of asthma is an
underrecognized treatable trait, associated with worse lung function and asthma control. The …

Noninvasiveness, low cooperation demand and the potential for detailed physiological
characterisation have promoted the use of oscillometry in the assessment of lung function …

This study was undertaken to determine whether a smaller lung volume or a stiffer lung
tissue accounts for the greater lung elastance of C57BL/6 than BALB/c mice. The …

Objectives: Elucidate how the degree of ventilator-induced lung injury due to atelectrauma
that is produced in the injured lung during mechanical ventilation is determined by both the …

The forced oscillation technique (FOT) is a non-invasive method to assess airway function
by emitting oscillatory signals into the respiratory tract during tidal ventilation. This opinion …

Pulmonary diseases represent four out of ten most common causes for worldwide mortality.
Thus, pulmonary infections with subsequent inflammatory responses represent a major …

We are currently limited in our abilities to diagnose, monitor disease status and manage
chronic airway disease like asthma and chronic obstructive pulmonary disease (COPD) …

Background Animal models and, in particular, mice models, are important tools to
investigate the pathogenesis of respiratory diseases and to test potential new therapeutic …