Membrane protein-based biosensors

N Misawa, T Osaki, S Takeuchi - Journal of the Royal …, 2018 - royalsocietypublishing.org
This review highlights recent development of biosensors that use the functions of membrane
proteins. Membrane proteins are essential components of biological membranes and have a …

Pesticide vapor sensing using an aptamer, nanopore, and agarose gel on a chip

S Fujii, A Nobukawa, T Osaki, Y Morimoto, K Kamiya… - Lab on a Chip, 2017 - pubs.rsc.org
A pesticide vapor sensor was developed using an agarose gel-based chip containing a
nanopore sensing system. Vaporized omethoate was detected by the absorption into the …

Recent advances in ion-channel probes for nanopore sensing: Insights into the probe architectures

EA Hussein, B Rice, RJ White - Analytica Chimica Acta, 2022 - Elsevier
This review introduces the recent advances in the nanopore sensing platform, ion channel
probes (ICPs), with a particular focus on the different probe design (2011–2022). The use of …

Investigating daptomycin–membrane interactions using native ms and fast photochemical oxidation of peptides in nanodiscs

DJ Reid, T Dash, Z Wang, CA Aspinwall… - Analytical …, 2023 - ACS Publications
Daptomycin is a cyclic lipopeptide antibiotic that targets the lipid membrane of Gram-positive
bacteria. Membrane fluidity and charge can affect daptomycin activity, but its mechanisms …

Surface modification of glass/PDMS microfluidic valve assemblies enhances valve electrical resistance

X Wang, MT Agasid, CA Baker… - ACS applied materials & …, 2019 - ACS Publications
Microfluidic instrumentation offers unique advantages in biotechnology applications
including reduced sample and reagent consumption, rapid mixing and reaction times, and a …

Expression, purification, and electrophysiological characterization of a recombinant, fluorescent Kir6. 2 in mammalian cells

MT Agasid, X Wang, Y Huang, CM Janczak… - Protein expression and …, 2018 - Elsevier
The inwardly rectifying K+(Kir) channel, Kir6. 2, plays critical roles in physiological
processes in the brain, heart, and pancreas. Although Kir6. 2 has been extensively studied …

Improving Stability and Preparation Efficiency of Electrophysiological Sensors

Z Wang - 2023 - search.proquest.com
Pipet aperture-based electrophysiological (EP) sensors have emerged relatively recently as
powerful bioanalytical tools. Taking advantage of the ligand specificity and inherent high …

Protein sensing device with multi-recognition ability composed of self-organized glycopeptide bundle

M Arai, T Miura, Y Ito, T Kinoshita… - International Journal of …, 2020 - mdpi.com
We designed and synthesized amphiphilic glycopeptides with glucose or galactose at the C-
terminals. We observed the protein-induced structural changes of the amphiphilic …

Metal Nanoneedle-based Ion Channel Probes for Localized Molecular Sensing

EAH Khalil - 2023 - search.proquest.com
The use of ion channel proteins has emerged in different applications to understand the
dynamics of many biological processes and characterize or detect biomolecules. As such …

Biomaterial Control of Cell Forces to Enable Intercellular Communication During Vasculogenic Assembly

C Davidson - 2022 - deepblue.lib.umich.edu
The ability of cells to communicate and coordinate their activity is crucial to the development
and homeostatic function of all tissues. In addition to the well-established means of …