The promising interplay between sonodynamic therapy and nanomedicine

R Canaparo, F Foglietta, N Barbero, L Serpe - Advanced Drug Delivery …, 2022 - Elsevier
Sonodynamic therapy (SDT) is a non-invasive approach for cancer treatment in which
chemical compounds, named sonosensitizers, are activated by non-thermal ultrasound …

Opening doors with ultrasound and microbubbles: Beating biological barriers to promote drug delivery

J Deprez, G Lajoinie, Y Engelen, SC De Smedt… - Advanced drug delivery …, 2021 - Elsevier
Apart from its clinical use in imaging, ultrasound has been thoroughly investigated as a tool
to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such …

CRISPR–Cas9 delivery strategies for the modulation of immune and non-immune cells

SK Alsaiari, B Eshaghi, B Du, M Kanelli, G Li… - Nature Reviews …, 2024 - nature.com
CRISPR–Cas9 genome editing technology is a promising tool for genetically engineering
immune cells and modulating immune systems. Although ex vivo genome editing of immune …

The emergence of cancer sono-immunotherapy

Y Yang, Y Cheng, L Cheng - Trends in Immunology, 2024 - cell.com
Owing to its remarkable ease of use, ultrasound has recently been explored for stimulating
or amplifying immune responses during cancer therapy, termed 'sono-immunotherapy' …

Nano-enhanced drug delivery and therapeutic ultrasound for cancer treatment and beyond

P Tharkar, R Varanasi, WSF Wong, CT **… - … in Bioengineering and …, 2019 - frontiersin.org
While ultrasound is most widely known for its use in diagnostic imaging, the energy carried
by ultrasound waves can be utilized to influence cell function and drug delivery …

The role of ultrasound-driven microbubble dynamics in drug delivery: from microbubble fundamentals to clinical translation

S Roovers, T Segers, G Lajoinie, J Deprez, M Versluis… - Langmuir, 2019 - ACS Publications
In the last couple of decades, ultrasound-driven microbubbles have proven excellent
candidates for local drug delivery applications. Besides being useful drug carriers …

Drug delivery by ultrasound-responsive nanocarriers for cancer treatment

K Entzian, A Aigner - Pharmaceutics, 2021 - mdpi.com
Conventional cancer chemotherapies often exhibit insufficient therapeutic outcomes and
dose-limiting toxicity. Therefore, there is a need for novel therapeutics and formulations with …

[HTML][HTML] Mechanisms underlying sonoporation: Interaction between microbubbles and cells

Y Yang, Q Li, X Guo, J Tu, D Zhang - Ultrasonics Sonochemistry, 2020 - Elsevier
The past several decades have witnessed great progress in “smart drug delivery”, an
advance technology that can deliver genes or drugs into specific locations of patients' body …

[HTML][HTML] Ultrasound-mediated drug delivery: sonoporation mechanisms, biophysics, and critical factors

CH YuAlfred - BME frontiers, 2022 - spj.science.org
Sonoporation, or the use of ultrasound in the presence of cavitation nuclei to induce plasma
membrane perforation, is well considered as an emerging physical approach to facilitate the …

[HTML][HTML] Manipulation with sound and vibration: A review on the micromanipulation system based on sub-MHz acoustic waves

Y Liu, Q Yin, Y Luo, Z Huang, Q Cheng, W Zhang… - Ultrasonics …, 2023 - Elsevier
Manipulation of micro-objects have been playing an essential role in biochemical analysis
or clinical diagnostics. Among the diverse technologies for micromanipulation, acoustic …